2: Limb Ulceration and Gangrene Flashcards

(56 cards)

1
Q

Define an ulcer

A

Break in skin or mucosa

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2
Q

What is the most common type of ulcer

A

Venous

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3
Q

What % of ulcers are venous

A

80

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4
Q

What are the three types of ulcer

A

Venous
Arterial
Neuropathic

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5
Q

What are the risk factors for arterial ulcers

A
Smoking 
HTN
DM
Age 
Obesity 
Physical inactivity 
FH
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6
Q

What are the risk factors for venous ulcers

A
Venous insufficiency 
Severe leg trauma
Pregnancy
Obesity 
Age
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7
Q

What are risk factors for neuropathic ulcers

A

Vitamin B12 deficiency

Diabetes mellitus

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8
Q

How will venous ulcers present clinically

A

V- SIG:
(Venous):

Shallow
Irregular borders
Granulating borders

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9
Q

Where are venous ulcers most often found

A

Medial malleolus

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10
Q

Are venous ulcers painful

A

Yes - pain is often worse towards end of the day

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11
Q

Describe symptoms of venous ulcers

A

Symptoms often precede the ulcer and include itching and aching

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12
Q

Where are arterial ulcers found

A

Distal sites - often areas of trauma or pressure areas

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13
Q

How will arterial ulcers present clinically

A

Deep, Well-defined borders

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14
Q

Are arterial ulcers painful

A

Yes

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15
Q

Describe symptoms prior to arterial ulcers

A

History of intermittent claudication

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16
Q

Where are neuropathic ulcers located

A

Pressure areas

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17
Q

What co-morbidities may someone with neuropathic ulcers have

A

Diabetes

Peripheral vascular disease

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18
Q

Are neuropathic ulcers painful

A

No

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19
Q

How are venous ulcers diagnosed

A

clinically

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20
Q

If a venous ulcer is present what may be used to confirm diagnosis of venous insufficeincy

A

Duplex US

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21
Q

What are the two most common sites of venous insufficiency

A

Sapheno-femoral

Sapheno-popliteal

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22
Q

Why may ABPI be performed for venous ulcers

A

To check for arterial component

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23
Q

If you suspect an ulcer is infected what should be done

A

Swab and culture

24
Q

What is done to investigate an arterial ulcer

A

ABPI

Duplex US and CTA

25
What is done to investigate a neuropathic ulcer
HbA1c Vitamin B12 X-ray - for osteomyelitis 10g mononeurofilament test to investigate extent of neuropathy
26
How are venous ulcers managed
- Raise legs - Exercises to increase calf muscles and venous return - Multicomponent compression bandaging
27
How long is multi compression venous bandaging kept on for
6m
28
How often is multi compression venous bandaging changed
1W
29
When can multi compression venous bandaging only be applied
If ABPI > 0.6
30
If individual with venous ulcer has venous insufficiency how may it be managed
Surgical intervention
31
If an individual has arterial ulcers how may they be managed
- If critical limb ischaemia refer for urgent vascular review - control RF: weight loss, supervised exercise program, diabetes control, anti-HTN, statin, anti-coagulants - angioplasty or bypass
32
how are neuropathic foot ulcers managed
- refer to diabetic foot clinic - regular podiatry inputs - surgical debridement of necrotic tissue
33
what is gangrene
type of tissue death due to lack of blood supply
34
what are the four types of gangrene
1. Wet 2. Dry 3. Gas 4. Fournier's
35
explain wet gangrene
Occurs following tissue infection with staphylococcus or streptococcus. Infection causes inflammation resulting in ischaemia and gangrene. The infection causes release of discharge - hence why it is wet
36
how will wet gangrene present clinically
Foul Smelling Discharge
37
how is wet gangrene managed
- IV antibiotics: benzylpenicllin + clindamycin - Debridement - May need amputation
38
What causes dry gangrene
Ischaemia due to vascular compromise such as from peripheral arterial disease
39
Explain appearance of dry gangrene
Presents as cold and black area - skin will then slough off
40
How should dry gangrene be managed
treat as critical limb ishaemia
41
what are the three features of gas gangrene
- Sepsis - Gas (Crepitus) - Myonecrosis
42
what causes gas gangrene
Clostridium pefringens infection - releases a-toxin
43
how may wounds become infected with clostridium pefringens
Contact of wound with soil or faeces
44
how will gas gangrene present clinically
- Starts with pain - Then systemic involvement (eg. Fever) - Cellulitis followed by purple vesicles and bullae - Crepitus on palpation of joints
45
what is necrotising fasciitis
infection that results in death/necrosis of subcutaneous tissue
46
how can necrotising fasciitis be classified
depending on causative organism
47
what is type 1 necrotising fascitis
caused by mix of aerobes and anaerobes
48
what is type 2 necrotising fascitis
caused by streptococcus pyogenes
49
how does necrotising fascitis present clinically
- acute-onset | - painful erythematous lesion (cellulitis) with pain out-keeping with clinical features.
50
how should necrotising fascitis be managed
- urgent surgical debridement | - IV antibiotics
51
what is fournier's gangrene
necrotising fascitis of the perineum
52
what can cause fourniers gangrene
- Mix anaerobes and aerobes | - Streptococcus pyogenes
53
how does Fournier's gangrene present in early stages
Fever | Pain out of proportion to clinical findings
54
as fournier's gangrene progresses how may it present
Haemorrhagic bullae Skin Necrosis Crepitus Septic shock
55
how is fournier's gangrene managed
Urgent surgical debridement IV antibiotics HDU transfer
56
what can be used to deride necrotic tissue
larval (maggot) therapy, hydrogels, surgery