2: Neurocognition Flashcards
What is dissociation?
A disruption in one component of mental functioning but no impairment of another (e.g., HM)
What is long-term potentiation?
- Changes in the ease at which two connected neurons will fire
- Lasts a few hours, days, or weeks
What is consolidation?
– Long-term change over days, weeks, months, or years
–> Small Scale
LTP between individual neurons
–> Large Scale:
LTP changes in assemblies of neurons over long periods of time
What is the function of the thalamus?
– Gateway to the cortex: almost all sensory messages (except smell) pass through the thalamus.
What is the function of the corpus callosum?
Primary bridge for messages to cross to the left and right hemispheres
What is the myelin sheath?
– Insulator for the axon
– Gaps – called nodes of Ranvier
» Note: not all neuron have myelinated sheath
– Mainly on neurons that are long (e.g., periphery of nervous system)
» Myelinated neurons are white matter (myelin is fat)
– Most cortical neurons (cognition) are unmyelinated
»These form what we call “Gray Matter”
What is the action potential?
- The change in electrical charge of a neuron from negative to positive
- This charge propagates from the dendrites and down the axon.
- Either a neuron fires or it does not
What is a synapse?
- The region in which the axon terminals of one neuron and the dendrites of another come together
- Convergence: many neurons may converge onto a single neuron
What are neurotransmitters?
- The chemical substance released into the synapse between two neurons
- Responsible for activating or inhibiting the next post- synaptic neuron
What is function of the hippocampus?
Implicated in storing new information in memory
What is the function of the amygdala?
Important for processing emotional qualities of information
What is the neocortex/cerebral cortex?
The top layer of the brain responsible for higher-level mental processes
- -Frontal lobe
- -Parietal lobe
- -Occipital lobe
- -Temporal lobe
What is contralaterality?
– Control of one side of the body is localized in the opposite-side cerebral hemisphere.
» The left hand, for instance, is largely under the control of the right hemisphere.
What are the hemispheric specialization?
Left hemisphere:
» language sounds, letters, words, speech, reading, writing, arithmetic, verbal memory, complex voluntary movement
Right Hemisphere:
» non-language sounds, geometric patterns, faces, nonverbal memory, prosody, narrative, inference, spatial processes, movements in spatial patterns.
What is the sensory and motor cortex?
- Sensory cortex: processing of sensory information from throughout the body
- Motor cortex: control of voluntary muscle movements
- further localization of function within the sensory and motor cortices
What is the dorsal and ventral pathway?
- Dorsal pathway: involved in “where” things are in space
- - Ventral pathway: Involved in “what” things are
What is a CT scan?
– Computerized-Axial Tomography; a bunch of X-rays that captures every layer/slice
What is an MRI scan?
– Gives clearer pictures of the structure of the brain
What is a single-cell recording?
Electrodes record the firing rate of individual cells
What are Electrocephalograms (EEG)?
– Electrodes are attached to the scalp to record the patterns of brain waves.
– Event-Related Potentials
» The momentary changes in electrical impulses when a particular stimulus is presented
What is transcranial magnetic stimulation (TMS)?
- An electrical field is targeted over specific brain areas to stimulate nerve cells
- This is a disruptive technique
What is Positron Emission Tomography (PET)?
- Image shows regions of the brain with heightened neural activity based on levels of blood flow.
- radioactive isotope injected and detected by scanner
- Cortical area(s) involved in the cognitive activity “light up”
What is a functional MRI (fMRI)?
- Similar to PET, but a more detailed image and does not involve a radioactive isotope
- Measures metabolic rates in specific brain area change
- Compare across different cognitive tasks
What are other measures of brain activity?
– Lesions
» Used by Sperry
» The site and extent of the brain lesion are important guides to the kind of disruption that is observed.
– Direct Stimulation
» Pioneered by Penfield
» The patient in brain surgery remained conscious and small electrical charges were administered to the exposed brain, thus triggering small regions
– Special Populations
Groups of people who have known differences in brain function