2- The anatomy and physiology of the kidney Flashcards

(34 cards)

1
Q

What is the renal capsule

A

Fibrous capsule around the kidney

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2
Q

What is the renal Cortex

A

The outer region of the kindey

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3
Q

What is the renal medulla

A

Inner region; composed of renal pyramids

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4
Q

What is the renal columns

A

Extension of cortex that dip into the medulla

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5
Q

What is the renal pelvis

A

Funnel-shaped sack; superior end of the ureter

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6
Q

What are minor and major calices

A

They are small and large tubes that merge to form the renal pelvis

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7
Q

What is the function of the renal artery

A

Branches off abdominal aorta, enters kidney through hilum

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8
Q

What is the function of segmental arteries

A

Branche off renal artery

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9
Q

What do interlobar arteries do

A

Branch off segmental arteries, flow between renal pyramids

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10
Q

What do arciform arteries do

A

Branch off interlobar arteries and arch around the renal pyramids

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11
Q

What do cortical radiate arteries do

A

Branch off arcuate arteries

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12
Q

What makes up the renal corpuscle

A

Glomerulus
Bowmans Capsules

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13
Q

What is the renal tubule and what is its function

A

It extends from the bowman’s capsule to the collecting duct, where distal tubules of several nephrons empty into a collecting duct.

The collecting duct continues through the medulla and drains through the renal papilla into a major calyx.

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14
Q

What are the two types of nephrons in the kidney.

A

Cortical nephron
Juxtamedullary nephron

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15
Q

What are structural features of cortical nephrons

A

Lie almost completely in renal cortex
Have short nephron loops
Renal corpuscles located near surface of kidney

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16
Q

What are the structural features of juxtamedullary nephrons

A

Have long nephron loops, that extend deep into the medulla

Renal corpuscles lie deep in renal cortex

Important in regulating water balance and urine excretion

17
Q

What is the function of the afferent arteriole

A

Branches off the cortical radiate arteries, each enters a different nephronW

18
Q

What is the function of the glomerulus

A

Cappilary cluster that branches from afferent arteriole (filters blood in each nephron )

19
Q

What is the function of the efferent arteriole

A

Arises from merging of glomerular cappilaries (transports blood that was not filtered by glomerulus)

20
Q

What is the fucntion of the peritubular cappilaries

A

Branches off the efferent arteriole; surrounds renal tubules.

21
Q

What is the function of the vasa recta

A

Branches off the efferent arteriole
Runs parallel to the tubules descending into the medulla
Forms capillary medulla networks and then return to the cortex

22
Q

What is the functions of the juxtaglomerular apparatus

A

A structure that regulates the secretion of the enzyme renin.
Monitors and adjusts blood pressure and NaCl content of filtrate.

23
Q

What is the macula dense

A

Tall, closely packed cells of the ascending limb
Monitors NaCl content of filtrate

24
Q

What do juxtaglomerlular cells do

A

Vascular smooth muscle cells of the ascending limb
Monitor blood pressure

25
What are the 3 processes of urine formation
Glomerular Filtration Tubular Reabsorption Tubular Secretion
26
What is the process of glomerular filtration in urine formation
Performed by specialised glomerular capillaries Water and small molecules are filtered Filtered fluid enters renal tubules and becomes tubular fluid
27
What is the process of tubular reabsorption
Transfer of filtered substances from renal tubules to peritubular capillaries Only reclaims useful substances while wastes continue to become urine
28
What is the tubular secretion phase of urine formation
Transfer of certain substances from peritubular capillaries to renal tubules Adds waste products and excess substances forming urine.
29
What is the composition of glomerular filtrate
Mainly water Glucose, amino acids Urea, Uric acid, creatine, creatine Ions
30
How is the net filtration pressure calculated
NFP= Forces favouring filtration - forces opposing filtration As long as the net flitration pressure in the glomerulus is positive, filtration will occur
31
What are forces favouring filtration
Glomerular capillary hydrostatic pressure
32
What are forces opposing filtration
Glomerular capillary colloid osmotic pressure Capsular hydrostatic pessure
33
What is the average adult GFR
125ml/min or 180L/day
34
What are the factors affecting GFR
GFR is directly proportional to the net filtration pressure, so anything that changes NFP will change GFR Changes in diameter of afferent or efferent arteriole