20

Question 1

Zoledronate (Zometa) has what mechanism?

Answer 1

Inhibits osteoclasts from binding to the ruffled border

Question 2

Denosumab (Xgeva) has what mechanism?

Answer 2

Inhibits RANK from binding to RANKL

Question 3

A patient comes in sayng that they are receiving treatment for osteoporosis and also has
active periodontal disease. Which of the following is true?

Answer 3

The risk of ARONG is low and it is more beneficial to do dental treatment
possibly with antibiotic prophylaxis

Question 4

Cancer cells have what characteristics

Answer 4

Low differentiation, high proliferation

Question 5

Question about correct prescription. Make sure it has dose, name, how many times per
day, how to take it and how much bottle will contain

Question 6

Question about how to dose a kid 37 lbs with amoxicillin 25kg/mg/day.

Answer 6

Answer was 150
mg/5 mL q8h

Question 7

Bevacizumab has what mechanism?

Answer 7

Stops VEG from binding to VEGF

Question 8

Which one of these is a monoclonal antibody?

Answer 8

Denosumab

Question 9

The drug is cisplatin. What type of drug is that?

Answer 9

Platinum compound

Question 10

Patient reports cold sensitivity and just started cancer treatment. What are they taking?

Answer 10

Oxaliplatin

Question 11

Which of the following does immunosuppression?

Answer 11

Methotrexate (other ones don’t do immunosuppression; ex: amoxicillin)

Question 12

Patient comes in and was told to tell you he is on cyclosporin. Which of the following
isn’t true?
a. He has gingival hyperplasia
b. He has high risk of infection
c. He will have issues with fluconazole
d. He is at risk for MRONJ

Answer 12

d. He is at risk for MRONJ

Question 13

Which of the following species is found in an abscess?

Answer 13

Bacteroides

Question 14

Bacterial infection has been around for >3 days. What do you give?

Answer 14

Augmentin

Question 15

If you’re using clauvulonic acid, it helps amoxicillin in bacteria that contain what?

Answer 15

Beta lactamases

Question 16

All of the following are beta lactams except
a. Penicillin
b. Amoxicillin
c. Cephalosporins
d. Azithromycin

Answer 16

Azithromycin

Question 17

All of these could cause MRONJ excpt what
a. Denosumab
b. Zolendronic acid
c. Bevacizumab
d. Tracrolimus

Answer 17

Tracrolimus

Question 18

Highest drug interactoins is seen with

Answer 18

Erthromycin

Question 19

Viridans Strep has the highest resistance to
a. Amoxicillin
b. Clindamycin
c. Azithromycin

Answer 19

c. Azithromycin

Question 20

21. Patient is immunosuppressed. What do you give them?

Answer 20

Amoxicillin

Question 21

Patient has HIV. What would you use to maintain them?

Answer 21

Combo with 4 drugs in it (listed all four)

Question 22

Why do you give amoxicillin three times a day?

Answer 22

It’s half life is 8 hours and it is time dependent

Question 23

What is the first organism seen in an early infection?

Answer 23

Gram + aerobe

Question 24

25. If a patient has this reaction to amoxicillin you will not give them cephalex

Answer 24

Blistering rash

Question 25

Which drug do you use for gram negatives, anaerobes and Bacteroides?

Answer 25

Augmentin

Question 26

What treats an anaerobic infection?

Answer 26

Metronidazole

Question 27

Which one is a drug reaction with warfarin?

Answer 27

Metronidazole

Question 28

Which drug is known to cause high risks of diarrhea?

Answer 28

Augmentin

Question 29

Which bacteria is known to cause C. diff?

Answer 29

Clindamycin

Question 30

What do you not give a pregnant person?

Answer 30

Doxycycline

Question 31

When would you give a person with infective endocarditis prophylaxis? a. Gingival manipulation b. Ortho movement c. Removable placement d. Radiographs

Answer 31

Gingival manipulation

Question 32

Which of the following heart conditions would be required to have infective carditis prophylaxis? a. Heart attack b. Prosthetic heart valve c. Heart failure

Answer 32

Prosthetic heart valve

Question 33

Antibiotics are indicated with

Answer 33

Systemic symptoms (fever)

Question 34

Which ones inhibits viral assembly?

Answer 34

Protein inhibitor

Question 35

Which of the following is not a life long disease?

Answer 35

Influenza A

Question 36

Which of the following has increased lipid accumulation and fat distrubtion?

Answer 36

Protease inhibitor

Question 37

What is the backbone of HAART?

Answer 37

NRTI

Question 38

What drug do you give someone who is immunosuppressed?

Answer 38

Amoxicillin

Question 39

CD4 count is below 50, what would you give them?

Answer 39

Azithromycin

Question 40

A patient takes azithromycin once a week. What disease do they have? a. HSV-1 b. HSV-2 c. HIV

Answer 40

HIV

Question 41

What drug lessens the effects of influenza?

Answer 41

Tamiflu (OSeltamivir)

Question 42

What is the role of an azole?

Answer 42

Blocks enzyme from lanosterol to ergosterol

Question 43

How does Zometa work with breast cancer?

Answer 43

Symbiotic relationship that further decreases bone destruction

Question 44

Which drug is used for patient that has xerostomia and mild oral candida?

Answer 44

Nystatin

Question 45

Nystatin has what role?

Answer 45

Binds to ergosterol in cell membrane

Question 46

Which of the following has drug interactions with Warfarin?

Answer 46

a. Tamiflu b. Amoxicillin c. Fluconazole?????

Question 47

What is a side effect of methotrexate?

Answer 47

Oral mucositis