20 Cards

Question 1

What electrolyte abnormality is associated with MDMA overdose?

Answer 1

Hyponatremia

Question 2

What should you prescribe with isoniazid to reduce the risk of Peripheral neuropathy?

Answer 2

Pyridoxine

Question 3

Meds that can cause gingival hyperplasia

Answer 3

MCC: phenytoin, cyclosporin, nifiedipine

Anticonvulsants: phenytoin, sodium valproate, phenobarbitone, ethosuximide
CCBS: nifedipine, amlodipine, verapamil, ditialzem
Immunosupprressants

Question 4

When to stop metformin

Answer 4

dose of metformin should be reviewed if the creatinine is > 130 micromol/l (or eGFR < 45 ml/min) and stopped if the creatinine is > 150 micromol/l (or eGFR < 30 ml/min)

Question 5

Which NSAID is contraindicated with any form of heart disease?

Answer 5

Diclofenac

Question 6

metabolic derangement in salicylate overdose?

Answer 6

Resp alkalosis followed by metabolic acidosis

Question 7

When to administer IV magnesium

Answer 7

: IV magnesium is usually given if <0.4 mmol/L or tetany, arrhythmias, or seizures

Question 8

What to give in TCA overdose

Answer 8

IV bicarbonate

Question 9

Management of cocaine toxicity

Answer 9

in general, benzodiazepines are generally first-line for most cocaine-related problems
chest pain:
benzodiazepines + glyceryl trinitrate
if myocardial infarction develops then primary percutaneous coronary intervention
hypertension: benzodiazepines + sodium nitroprusside
the use of beta-blockers in cocaine-induced cardiovascular problems is a controversial issue
the American Heart Association issued a statement in 2008 warning against the use of beta-blockers (due to the risk of unopposed alpha-mediated coronary vasospasm) but many cardiologists since have questioned whether this is valid
if a reasonable alternative is given in an exam it is probably wise to choose it

Question 10

Adverse effects cocain toxicity

Answer 10

Adverse effects
cardiovascular
coronary artery spasm → myocardial ischaemia/infarction
both tachycardia and bradycardia may occur
hypertension
QRS widening and QT prolongation
aortic dissection
neurological
seizures
mydriasis
hypertonia
hyperreflexia
psychiatric effects
agitation
psychosis
hallucinations
others
ischaemic colitis is recognised in patients following cocaine ingestion. This should be considered if patients complain of abdominal pain or rectal bleeding
hyperthermia
metabolic acidosis
rhabdomyolysis

Question 11

Liver transplantation criteria in paracetamol overdose

Answer 11

Liver transplantation criteria in paracetamol overdose: pH < 7.3 more than 24 hours after ingestion

Question 13

HRT choice for women at risk of VTE

Answer 13

Transdermal

Question 14

Meds that cause urticaria

Answer 14

Aspirin
Penicillins
NSAIDS
Opiates

Question 15

Meds that cause photosensitivity

Answer 15

Thiazides
Tetracyclines, sulphonamides, ciprofloxacin
Amiodarone
NSAIDS
Psoralens
Sulphonylureas

SAN LIGHT - Sulfonamides, amiodarone, NSAIDS, Loop diuretics, isotretinoin, griseofluvin, hydrochlorothiazide, tetracycline

Question 16

What may precipitate lithium toxicity

Answer 16

Dehydration
Renal failure
Diuretics, ACEi/ARBs, NSAIDS,metronidazole

Question 17

When to give PO activated charcoal for aspirin OD

Answer 17

Within a hour

Question 19

Syntocinon

Answer 19

Syntocinon is a synthetic version of oxytocin that is used in the active management of third stage of labour. It stimulates the contraction of the uterus reducing the risk of postpartum haemorrhage. It is also used to induce labour.

Question 20

Ergometrine

Answer 20

Ergometrine is an ergot alkaloid which is used as an alternative to oxytocin in the active management of third stage of labour. By constricting vascular smooth muscle of the uterus it can decrease blood loss.

Mechanism of action
stimulates alpha-adrenergic, dopaminergic and serotonergic receptors

Adverse effects
coronary artery spasm