20. Drugs used for heart failure Flashcards

1
Q

A patient is diagnosed with systolic heart failure and is given a drug an oral direct vasodilator since she i didn’t respond well to ACE-I. With her new medication what drug is contraindicated?

A. Losartan 
B. Sildenafil
C. Spironolactone 
D.Carvedilol
E Epoprostenol

RFA

A

Ans. B Sildenafil- is a boner drug like Viagra and is contraindicated in the use of Direct Vasodilators: Hydralazine + isosorbide dinitrate

A. Losartan- is an ARB and are usually given if patients have ACI-I cough

C. Spironolactone- is an Aldosterone antagonist and is usually used with ACE as a second line

D. Carvedilol is a B- blocker and is used is addition with ACEI for patients with heart failure

E. Epoprostenol- is a synthetic PGI wich lowers peripheral pulmonary and coronary resistance.

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2
Q

A 48 year old women is rushed to the hospital do to easy fatigue, dizziness and pooling of blood in her feet. After imaging it is concluded that here problem is do to stiffening of heart muscle that inhibits it from relaxing normally. After this revelation the medical term moves to make a list of medication to treat her. Which medication should they avoid using for this condition?

A. Glucagon 
B. Lisinopril 
C. Losartan 
D. Hydrochlorothiazide 
E. Milrinone

RFA

A

ANS. Milrinone- is a PDE III inhibitor it is a positive inotropic drug and by the patients description of the condition they have Diastolic HF(HFpEF) where positive inotropic drugs are contraindicated

A. Glucagon- is used for B-blocker overdose

B-Lisinopril- ACE-I is fist line

C. Losartan- ARB is fist line

D. Hydrochlorothiazide- a thiazide diuretic is also first line

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3
Q

A patient has an MI and goes into shock. What drug do you give to induce diuresis, cause a positive inotropic effect, and vasodilation? (MG)

A. Dopamine
B. Dobutamine
C. Amiodarone
D. Labetalol

A

A. Dopamine

low dose dopamine does these things bc it acts primarily on the beta1 receptors

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4
Q

Which of the following drugs does not aid in heart failure due to increase cAMP levels? (MG)

A. Milrinone
B. Inamrinone
C. Glucagon
D. Captopril

A

D. Captopril

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