2016 MCQ Flashcards

1
Q

What condition would a patient have if their LFTs showed raised bilirubin and CRP only

A

Gilbert’s syndrome

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2
Q

What cell is missing in a patient who needs vitamin B12 injections?

A

Parietal cells (produce intrinsic factor)

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3
Q

What are the surface markings of the gall bladder?

A

Junction between costal margin of 9th ribs and lateral margin of rectus abdominis muscle

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4
Q

What are the stages of eGFR?

A
  1. > 90
  2. 60-89
    3a. 45-59
    3b. 30-44
  3. 15-29
  4. <15
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5
Q

What are the units of eGFR?

A

mL/min

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6
Q

What is the main blood supply of the pelvic viscera?

A

Internal iliac arteries

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7
Q

What artery branches to give the middle suprarenal arteries?

A

Abdominal aorta

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8
Q

Which artery passes through the transverse mesocolon?

A

Middle colic

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9
Q

In chronic myeloid leukemia, which enlarged organ can be palpated at the left with a notch?

A

Spleen

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10
Q

What is the rate limiting step for cortisol production?

A

Cholesterol to pregenolone

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11
Q

What vein forms oesophageal varices?

A

Left gastric vein

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12
Q

What connects the primary and secondary hypophyseal plexuses?

A

The hypophyseal portal vein

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13
Q

In a tumour of the adrenal medulla, production of what increases?

A

Catecholamines

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14
Q

How does the kidney compensate for acidosis?

A

Increased bicarbonate absorption, increased glutamine breakdown (produces bicarbonate)

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15
Q

What is the main anterior relation to the right kidney?

A

Liver

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16
Q

What is the mechanism of action of carbimazole?

A

Inhibition of thyroid peroxidase

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17
Q

What is the first clinical sign of diabetic nephropathy?

A

Proteinuria

18
Q

What serum change occurs when podocytes are damaged?

A

Low serum albumin

19
Q

What drug directly stimulates beta cells to increase insulin production?

A

Sulfonylureas

20
Q

What is produced by chief cells?

A

Pepsinogen

21
Q

What does orlistat do?

A

Inhibits pancreatic lipase; stops lipid absorption

22
Q

What will be seen on a plain upright radiograph in a patient with perforation and air leakage caused by a duodenal ulcer?

A

(enlarged) suphrenic space

23
Q

What skin condition is associated with coeliac disease?

A

Dermatitis herpetiformis

24
Q

What process occurs in zone 3 of the hepatic acini?

A

Glutamine synthesis

25
Q

What does the urogenital septum divide?

A

Cloaca

26
Q

What is homologous to the clitoris in males?

A

Glans penis

27
Q

What happens to the bladder in thoracic spinal injury?

A

Internal urethral sphincter does not contract

28
Q

Which GLUT responds to insulin?

A

GLUT 4

29
Q

What hormone is responsible for the maintenance of the corpus luteum if fertilisation occurs?

A

hCG

30
Q

What level of fasting glucose indicates diabetes?

A

more than 7.0 mmol/L

31
Q

What is the covering of the testis that is derived from the peritoneum?

A

Tunica vaginalis

32
Q

Which cells in the testis undergo meiosis 1?

A

Primary spermatocytes

33
Q

What embryological structure is the adrenal medulla derived from?

A

Neural crest

34
Q

What cells produce MSH in the anterior pituitary?

A

Corticotrophs

35
Q

What is the gold standard diagnostic test for Cushing’s syndrome (excess cortisol)

A

Dexamethasone suppression test

36
Q

Which artery supplies the pelvic floor muscles?

A

Internal iliac artery

37
Q

In the GI tract, which ion is glucose co-transported with?

A

Sodium

38
Q

Which drug acts on the final stage of acid secretion in parietal cells of the stomach?

A

PPIs

39
Q

What type of structure is the plicae circulars?

A

Permanent folds

40
Q

What is the order of tubules in which sperm travel after the seminiferous tubules?

A

Straight to rete testis to efferent ductules to epididymus

41
Q

What is the channel in the thick ascending limb?

A

NCCK