Micro - Fungal Flashcards

1
Q

Define Dimorphic

A

Yeast at 37 C (body temp), mold at room temp

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2
Q

Define DermatoPHYtoses

A

infect skin, hair, and nails

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3
Q

Define DermatoMYCoses

A

Invasive fungal infections of the skin. Includes primary and secondary colonizations

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4
Q

Define Dematiaceous fungi

A

Hyphae and/or spores darkly pigmented

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5
Q

Malassezia species Mycosis

A

Pityriasis versicolor

Superficial fungi

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6
Q

Hortaea werneckii Mycosis:

A

Tinea nigra

Superficial fungi

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7
Q

Trichosporon spp Mycosis:

A

White piedra

Superficial fungi

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8
Q

Piedraia hortae Mycosis:

A

Black Piedra

Superficial fungi

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9
Q

Malassezia furfur/Pityriasis versicolor lab tests

A

Dimorphic, Lipophilic (grow on solid media overlaid with olive oil)
Requires LONG-chain fatty acids for growth

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10
Q

Oval scaly macules/papules. Hypo/Hyper pigmentation
Patches where sebaceous glands present
Fluoresces bright yellow with wood lamp
Short, unbranched hyphae with round spores (KOH)
“Spaghetti and meatballs”

A

Malassezia furfur aka Pityriasis versicolor

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11
Q

Branched septate hyphae and budding yeast cells with melanized cell walls. A Dermatiaceous fungus.
Brownish to grey patches on palms or soles

A

Hortae (Exophialia) werneckii

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12
Q

Soft (ish) white nodules on hair (hyphae when crushed)

Urease positive

A

Trichosporon spp - White piedra

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13
Q

Ectotrhix

A

Stone-like formation on scalp and facial hair (NOT genital) - Piedraia hortae - BLack piedra

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14
Q

Cutaneous fungi (Microsporum spp, TrichoPHYton spp, and Epidermophyton floccosum) all cause:

A

Dermatophytosis (ring worm)

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15
Q

Virulence factor of Tineas

A

Keratinases

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16
Q

Tinea corporis: Location

A

Nonhairy, smooth skin, Trunk

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17
Q

Tinea corporis: Clinical features

A

Circular patches with advancing red, vesiculated border and central scaling, pruritic

18
Q

Fungi responsible for Tinea corporis

A

T. Rubrum *

E. Floccosum

19
Q

Tinea Pedis: Location

A

Interdigital spaces on feet

20
Q

Tiena pedis: Clinical features

A

Acute: Itching, red, vesicular
Chronic: itching, scaling fissures
“Athletes foot” - men, wearing shoes

21
Q

Fungi responsible for Tinea pedis

A

*T. Rubrum
T. Mentagrophytes
E. Floccosum

22
Q

Tinea cruis: location

A

Groid

23
Q

Tinea cruis: Clinical

A

Erythematous scaling lesion in intertriginous areas, pruritic

24
Q

Tinea cruis: Fungi responsible

A

*T. Rubrum
T. Mentagrophytes
E. Floccosum

25
Q

Tinea cruris differential: Erythrasma

A

Caused by Corynebacterium minutissimum

Fluoresces coral red (T. cruis does NOT fluoresce)

26
Q

Tiena cruris differential: Candida

A

Affects skin ON scrotum and thick

T. cruis begins on skin opposite of scrotum - not ON the scrotum itself

27
Q

Tinea infections - Hyphae location (histo level)

A

Stratum corneum

28
Q

Tinea capitis: Location, clinical features, Fungi responsible

A

Scalp hair
Circular bald patches w/short hair stubs or broken hair w/I hair follicles
Most common in US: T. Tonsurans (T. Mentagrophytes, M. Canis)

29
Q

Tinea Barbae: Location, Clinical, Fungi responsible

A

Beard Hair
Edematous, erythematous lesions
T. Mentagrophytes

30
Q

Tinea Unguium “Onychomycosis”

Location, Clinical features, Fungi responsible

A

Nail
Nails thickened or crumbling distally, discolored, lusterless
T. rubrum, T. mentagrophytes, E. Floccosum

31
Q

Dermtophytid “id Reaction”

Location, Clinical features, Fungi responsible

A

Usually sides and flexor aspects of fingers
Pruritic vesicular to bullous lesions; Most commonly associated with tinea pedis
Fungi responsible: NO fungi in lesion

32
Q

Which cause of tinea capitis fluoresce under Wood’s Lamp

A

Microsporum (Trichophyton does NOT)

33
Q

What is a Kerion?

A

Intense, painful, boggy, suppurative reaction associated with cervical lymphadenopathy.
Found at the nape of the neck

34
Q

What is needed to control Candida

A

T-cell response

35
Q

Sprothrix schenckii. Mycosis =?

A

Sporotrichosis

36
Q

Phialophora Verrucosa

Fonsecaea pedrosoi. Mycosis =?

A

Chromoblastomycosis

37
Q

Pseudallescheria boydii

Madurella mycetomatis Mycosis =?

A

Mycetoma

38
Q

Exophiala
Bisporais Mycosis = ?
Exserohilum

A

Phaeohyphomycosis

39
Q

“Drunken rose gardener’s disease”
Initial lesion = papule
Follows LYMPHATICS - CHAIN OF NODULES

A

Sporothrix schenkii

Dimorphic fungus

40
Q

Local swelling

Interconnecting sinuses that contain granules (granules = microcolonies of the agent embedded in tissue)

A

Mycetoma

41
Q

Mycetoma colors and significance

A

White: P. boydii
Black: M. grisea, E. jeanselmei
Dark red - black: M. mycetomatis

42
Q

Tropics
Feet exposed to infected soil
Warty, friable granuloma on leg
“Cauliflower like”
Starts as smooth papule, then becomes verrucous lesion
Pustules may contain pigmented fungal cells (MEDLAR BODIES)

A

Chromoblastomycosis