21 Cardiac muscle heart as a pump Flashcards
(23 cards)
Muscle tissue that contains intercalated discs
Cardiac muscle (found in myocardium)
A single cell or cytoplasmic mass containing several nuclei, formed by fusion of cells or by division of nuclei. Found in cardiac muscle
Syncytium
Ventricular muscle contraction. Stimulated by an action potential
Systole
Ventricular muscle relaxation. Na+/K+/Ca++ gradients are reestablished
Diastole
aka the atrial wave. Corresponds to atrial depolarization
P wave
This complex indicates ventricular depolarization, which triggers contraction of the ventricles
QRS complex
Represents the repolarization of the ventricles
T wave
The last phase of diastole.Atrial contraction pumps the remaining 10% of blood into the ventricles in this phase.
AV valves open
Aortic & pulmonic valves close
The S4 heart sound occurs
(Phase 1) Atrial contraction
The first phase of systole. Contraction of the ventricles occurs with no corresponding volume changing. AV and semilunar valves are closed S1 sound occurs End diastolic volume is found in LV C wave occurs
(Phase 2) Isovolumetric contraction
The blood contained in the ventricles is ejected into the aorta (and lungs in the right heart).
Aortic pressure spikes
Ventricular pressure spikes
V wave occurs
Ventricular volume decreases significantly
Semilunar valves are open, AV valves are closed
(Phase 3) Rapid Ejection
Blood continues to leave the ventricles (however, less forcefully). Decrease in aortic pressure V wave End systolic volume is reached T wave occurs
(Phase 4) Reduced Ejection
First phase of diastole.
End systolic volume remains in LV
Aortic pressure: dicrotic notch aka incisural
Ventricular pressure: decreases dramatically
Atrial pressure: Increases steadily
S2 sound occurs
All valves are closed
(Phase 5) Isovolumetric relaxation
Av valves open during this phase. Aortic pressure: decreases Ventricular pressure: no change Atrial pressure: decreases slightly Ventricular volume: increases S3 sound occurs V wave ends
(phase 6) Rapid filling
Slow, passive ventricular filling.
Ventricular pressure: remains constant
Atrial pressure: remains constant
Ventricular volume: increases steadily (to approach 110 mmHg or ~90% full)
Aortic pressure: Decreases to approx 80 mmHg
AV valves remain open
(phase 7) Reduced filling
Make an equation sheet
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1) Pressure during filling of the ventricle. 2) Stress in the wall of the left ventricle at the end of diastole.3) The end diastolic pressure when the ventricle has become filled
Preload
1) pressure in the aorta leading from the ventricle. 2) Stress in the wall of the left ventricle during ejection
Afterload
An increase in EDV (end diastolic volume) leads to an increase in stroke volume
Frank-Starling mechanism
T/F. Excess serum K+ concentration increases cardiac contractility by increasing resting membrane potential & the intensity of the action potential
False. Excess K+ decreases contractility by decreasing resting membrane potential & intensity of the action potential
T/F. Excess serum Ca++ causes spastic contraction
True
T/F. Low serum Ca++ causes cardiac dilation (flaccidity)
True
Sound present with reduced ventricular compliance (ventricular hypertrophy)
S4
T/F. Blood is always entering the left atrium from the lungs
True