Tumors Flashcards

1
Q

location of osteiod Osteoma

A

50% in tib/fib,
spine,
posterior elements

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2
Q

Age of osteiod Osteoma

A

2nd , 3rd decace

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3
Q

Clinical osteiod Osteoma

A

pain worst at night
relieved with salicylates 6-24 months before diagnosis
painful scoliosis
If intraarticular it may mimic JRA w/synovitis and joint effusion

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4
Q

Radiology findings of osteiod Osteoma

A

Reactive sclerosis
lucent nidus less than 1cm
may have central calcification
misleading MR

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5
Q

Tx for osteiod Osteoma

A

surgical radiofrequency ablation

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6
Q

Location of osteoblastoma

A

long bones 40% in sline

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7
Q

age osteoblastoma

A

2nd , 3rd decade

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8
Q

clinical findings of osteoblastoma

A

rarely agressive

pseudomalignant

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9
Q

Radiology osteoblastoma

A
Giant Osteiod osteoma 
lucent nidus greater than 1.5 cm 
may have multiple internal calcifications 
maybe expansile 
less reactive sclerosis than OO
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10
Q

Location for osteosarcoma: classic medullary

A

medullary metaphyseal
40% femur
>50% at knee

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11
Q

age of osteosarcoma: classic medullary

A

10-25 yo

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12
Q

clinical findings of osteosarcoma: classic medullary

A

pain months before diagnosis

Elevated alkaline phosphate

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13
Q

Radiology findings of osteosarcoma: classic medullary

A

cloud like dense bone formation
may have extraosseous mass
sunburst
speculated periosteal reactive often with codman’s triangle

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14
Q

tx for osteosarcoma: classic medullary

A

poor prognosis (30% 5 yr) if presents with skip lesion of 4 lung mets ; isolated lesion 75% 5 yr survival

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15
Q

location of parosteal osteosarcoma

A

2/3 distal femoral metaphysis

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16
Q

age of parosteal osteosarcoma

A

27 YO , 5-10 years older than medullary

female >male

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17
Q

clinical findings for parosteal osteosarcoma

A

mass w/dull aching pain

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18
Q

radiology findings of parosteal osteosarcoma

A

amoprphous

cloud of mineralization in lobulated surface mass

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19
Q

Tx for parosteal osteosarcoma

A
better prognosis than medullary
5 yr survival >90%
low grade 
chemo not indicated 
Best prognosis if no medullary extension
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20
Q

age for periosteal osteosarcoma

A

diaphysis

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21
Q

age for periosteal osteosarcoma

A

same age as medullary

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22
Q

clinical findings for periosteal osteosarcoma

A

1-2% of OS

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23
Q

Radiology findings of periosteal osteosarcoma

A

rare surface lesion
Periosteal reaction
soft tissue mass

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24
Q

tx for periosteal osteosarcoma

A

slightly better prognosis than medullary

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25
Q

clinical findings for Telengiectatic osteosarcoma

A

5% of OS

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26
Q

Radiology findings of Telengiectatic osteosarcoma

A

Usually osteolytic
frequent fluid filled levels
spider web blood vessels so blood inside the bone

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27
Q

Tx for Telengiectatic osteosarcoma

A

prognosis same as classicl OS

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28
Q

clinical findings in osteosarcoma in paget’s dz

A

occurs in 1% of paget pts
rule of 1
classic finding: their hat wont fir anymore

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29
Q

tx for Telengiectatic osteosarcoma

A

poor prognosis 5 yr survival 3-8%

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30
Q

location of Endchondroma

A

50% in hands and feet

also long flat bones

31
Q

age of Endchondroma

A

wide age range

32
Q

clnical findings of Endchondroma

A

painless unless fx or malignant change
Ollier’s: multiple enchondromatosis
usually presents as a growth disturbance in childhoold , not inherited
30% malignant tranformation
Mafucci’s multiple enchondromas w/soft tissue hemangiomas , all pts will die of cancer

33
Q

radiology findings of Endchondroma

A

benign, intramedullary cartilaginous lesion, geographic lesion w/punchtate calcified matriz
maycause scalloping or expansion

34
Q

location of Juxtacortical chondroma

A

most in small tubular bones of hands & feet

35
Q

age of Juxtacortical chondroma

A

usuallypain and swelling soft mass (50% calcify)

36
Q

radiology finding of Juxtacortical chondroma

A

solid , benign cartilage tumor that can erode underlying bone , erosion and saucerization of underlying bone

37
Q

location of chondroblastoma

A

Epiphysisi

38
Q

age of chondroblastoma

A

2nd, 3rd decade

39
Q

clinical findings of chondroblastoma

A

benign

pain and joint effusion

40
Q

radiology findings of chondroblastoma

A

usually geographic, 50% have calcifications

41
Q

location of chondromyxoid fibroma

A

76% in LE metaphysis

42
Q

age of chondromyxoid fibroma

A

wide range most in 2nd decade

43
Q

clinical findings of chondromyxoid fibroma

A
very rare (1% bone tumores) 
vague pain
44
Q

Radiology findigns of chondromyxoid fibroma

A

multiloculated
geographic with sclerotic margins
no calcifications

45
Q

location of Osteochondroma

A

metaphysis

points away from joint

46
Q

age of Osteochondroma

A

usually adolelscence

47
Q

clinical findigns of Osteochondroma

A
common 
decreased ROM 
malignat degenration suspect when growth afer skeletal maturity or pain ,cartilage cao > 2cm in adults ir 3 cm in children 
multiple hereditary ostechondromatosis, 
multiple exostoses 
autosomal dominant
incomplete penetrance
48
Q

Radiology findings of Osteochondroma

A

cartilage capped bony excrescence ( like bony exostosis )

cap may calcify

49
Q

age for Bizarre parosteal osteochondromatosis (Nora’s lesion ) age

A

20-30s

50
Q

Bizarre parosteal osteochondromatosis ( Nora’s lesion ) clinical

A

benign lesion but w/ high local recurrence

51
Q

location for chondro sarcoma

A

metaphysis

52
Q

age for chondro sarcoma

A

40

53
Q

clinical chondro sarcoma

A

primary ( de novo)
secondary from osteochondroma enchondroma, etc
pain

54
Q

Radiology chondro sarcoma l

A

lucent metaphyseal lesion with calcifications may have sclerotic margins

55
Q

location for clear cell chondrosarcoma

A

epiphysis

56
Q

age for clear cell chondrosarcoma

A

40

57
Q

clinical clear cell chondrosarcoma

A

resembles chondroblastoma but pt is 40 yo

58
Q

radiology of clear cell chondrosarcoma

A

dedifferentiated chondrosarcoma

both low grade and high grade tissue present

59
Q

location for non ossifying fibroma

A

medullary
LE
arise at growth plate and migrate to diaphysis with pt growth

60
Q

age of non ossifying fibroma

A

common 40% of children

61
Q

clinical non ossifying fibroma

A

asymptomatic until fracture; natural hx=regresion;
jaffe-campanacci syndrome = multiple NOFs with cafe au lait spots
NF1- multile NOFs

62
Q

Radiology of non ossifying fibroma

A

geographic
sclerotic border
DO NOT BIOPSY!!!!!

63
Q

location of fibrous dysplasia

A

usually unilateral

64
Q

clinical fibrous dysplasia

A

presents w/ deformity
sometimes pain secondary to fx
albright’s syndrome = cafe au lait
polyostotic FD, endocrine abnormalities eso precocious puberty
Mazabrauds’ syndrome = polyostotic FD w/ intramuscular myxomas

65
Q

Radiology of fibrous dysplasia

A
benign firboosseous lesion of bone 
25% polyostotoc 
usually geographic
ground glass matruc 
can have dense areas of calcifications 
MR: hypointense on T1
hyperintense on T2 but frequently heterogenous enhances with gadolinium BUT may have custic non enhancing areas
66
Q

ocation for osteofibrous dysplasia (ossifying fibroma )

A

intracortical
FD
almost always tibia

67
Q

age for osteofibrous dysplasia (ossifying fibroma )

A

early childhood

becomes stable

68
Q

clinical osteofibrous dysplasia (ossifying fibroma )

A

usually painless

may be related to adamantinoma

69
Q

radiology of osteofibrous dysplasia (ossifying fibroma )

A

ground glass cortical lesion

70
Q

location for fibrisarcoma & mfh

A

metaphysis

age for

71
Q

age for fibrisarcoma & mfh

A

3rd-6th decade

72
Q

clinical for fibrisarcoma & mfh

A

may arise secondary to other lesions including infarcts

73
Q

radiology for fibrisarcoma & mfh

A

agressive lytic lesion
no matric
no periosteal rx