2.2 Cell membranes Flashcards

1
Q

What is CF caused by?

A

A faulty transport protein in surface cell membranes of epithelial cells

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2
Q

What is the role of cell membranes

A

They controll what pass through them

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3
Q

What are the six main elements which make up the surface cell membrane

(And their role)

A
  • Phospholipid bilayer - acts as barrier, prevents substances entering/exiting.
  • Carrier proteins - Move substances across membrane
    * Channel proteins - Allows molecules that are too hydrophilic/large to pass through membrane
    Glycolipids - Involved in cell signalling/recognition
  • Glycoproteins - Involved in cell singalling/recognition
    * Cholesterol - Steroid molecule blocks gaps in membrane
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4
Q

How do channel proteins move molecules

A
  • They create a hydrophilic “tunnel” for molecules to pass through
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4
Q

How do carrier proteins move molecules?

A
  • Molecules bind to protein
  • Protein changes shape, moving substance across membrane.
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5
Q

What process are both carrier and channel proteins involved in.

Define process

A

Facilitated diffusion - the movement of particles form an area of high to low concentration involving transport proteins.

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6
Q

What does cholesterol reduce in the cell membrane?

A

The fluidity of the membrane

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7
Q

What are the 4 main ways substances pass through the cell membrane

A
  • Diffusion
  • Osmosis
  • Active transport
  • Exocytosis
  • Endocytosis
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8
Q

Which particles are able to diffuse through the Phospholipidbilayer?

and example

A
  • Hydrophobic particles
  • Small particles
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9
Q

When does diffusion stop

A

When the concentration of the particle is the same either side of the membrane.

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10
Q

Is diffusion against or with concentration gradient?

A

With

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11
Q

Which 2 structures are involved with facilitated diffusion

A
  • Carrier protiens
  • Channel proteins
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12
Q

Is facilitated diffusion against or with concentration gradient?

A

With

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13
Q

Define osmosis

A

The movement of water particles from a solution with a lower concentration of a solute to a solution with a higher conecentration of a solute.

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14
Q
A
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15
Q

Define isotonic

A

Solute concentration is same inside cell

(Osmosis stops when isotonic)

16
Q

What is the energy molecule involved in active transport + how does it work (think pumps)

A
  • ATP (adenosine tri phosphate)
  • 1 phosphate released and bonds to water - releases energy which drives shape change of carrier protein.
17
Q

Differece between exo/endocystosis

A

Exocytosis - Transports substances out of cell in vesicles (EXITS)
Endocytosis - Transports substances into cell in vesicle (Enters)

(Both inovled in bulk transport / large molecules)

18
Q

Example of Exo/Endocystosis

A
  • Exo-Insulin into blood
  • Endo - Cholesterol taken up by cells
19
Q

2 forms of Endocytosis

A
  • Phagocytosis (extensions from membrane)
  • Pinocytosis (cell membrane invaginated)
20
Q
A
21
Q

Example fo Active transport in cell membrane

A

NA+/K+ pump