Intraocular Inflammations Flashcards

0
Q

How is uveitis classified

A

By location.

  1. Anterior uveitis - iritis, iridiocyclitis, cyclitis
  2. Intermediate uveitis- pars planitis
  3. Posterior uveitis- choroiditid, chororetinitis, retinochoroiditis, retinitis
  4. Pan uveitis- affecting uvea

Classification by duration.

  1. Acute. Less that 6weeks. Maybe recurrent
  2. Chronic. More than 6weeks. White eye? Mild or no sx
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1
Q

How would one get uveitis

A

Genetics
Infection
Trauma

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2
Q

Anterior uveitis

A

Most common. Espesh in younger Px
Risk factors include- systemic conditions. Previous history. Blunt trauma?
Associated with syphillis, herpes simplex, herpes zoster, tb, hypermature cataract
Usually unilateral, assymetrical, red eye, painful, sight threatening.

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3
Q

Acute anterior uveitis - IRITIS

A
Red eye
Pain
Blurred Vision
Photophobia 
Tearing 

Reduced va due to corneal odeama, anterior flare and cells and cystoid macular odeama.
6/6-6/9 is mild
6/9-6/30 is mod
Less than 6/30 is severe va loss

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5
Q

What would u see on slit lamp for anterior uveitis

A
Peribal injection - red eye 
Ac flare and cells
Keratitic precipitates 
Pupil miosis- slugish fixed pupil
Hypopyon- strong inflammation 
Band keratopathy- deposits in cornea 
Fibrin in ac
Cells in anterior vitreous
Peripheral anterior synechie 
Posterior synichea 
Rubeosis irisdis
Mutton fat kp 
Iris nodules
Boggy iris- swelled
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6
Q

What does tonometry for anterior uveitis show

A

Either decreased, increased or just the same.

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7
Q

Gonioscopy on anterior uveitis

A

peripheral anterior synechiae

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8
Q

Whats the goals in managing anterior uveitis

A
preserve vision
relieve ocular pain
eliminate any infection- identify the actual sour
prevent formation of synechiae
control IOP
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9
Q

How would u manage anterior uveitis

A

Topical corticosteroid therapy:

  • to reduce inflammation
  • to reduce exudate leakage
  • increase cell wall stability
  • inhibit circulation of lymphocytes
  • inhibit lysozyme release by granulocytes

Cyclopegia: relieve pain and prevent posterior synechiea and stabilise blood aqueous barrier

Systemic steroid therapy

Systemic NSAID therapy (asprin/iburprofen)

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10
Q

How would u review a px with anterior uveitis

A

initial- after a few days- good if sx and signs reduced

Review after depending on severity and inflammation, risk of complications and compliance

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11
Q

Optoms role in anterior uveits DDD

A

Detect- H+S, check IOP, examination
Differentiation
Diagnose

REFER IMMEDIATELY
Could co-manage- monitor IOP, sunglasses, near add rx for cyclopegia?

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12
Q

Whats intermediate uveitis

Vitritis

A

Inflammation of vitreous and anterior retina
white eye
but blurry va
floaters
white opacities- snow balls/snow banks
cystic macular odeama and optic disk odeama

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13
Q

What are the complications of intermediate uveitis

A
Synechiae
band keratopathy
glaucoma
cataract
neovas 
heammorages
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14
Q

How would u manage intermediate uveitis

A

usually managed in hospital- follow up every 1-4 weeks
for cystic macular odeama- consider fl angiography
If va- good- monitor
if va detoriated- topical/periocular steroids- monitor IOP for px on steroids
immunosuppressive therapy

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15
Q

Sx of posterior uveitis

A

Blurred vision
floaters
pain?
photophobia?

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16
Q

What are the signs of posterior uveitis

A
cystic macular odeama
neovas
infiltrates
vitreitis
mild anterior segmant inflammation
vascular sheating
17
Q

Fuch’s Iridocyclitis

A
Insidious onset- affects young px
Iris heterochromia
Keratitic Precipitates
NO posterior synechiae
Spontaneous haemorrhage in the AC during cataract operation

Complications: cataract, glaucoma

18
Q

Posner Schlossman Syndrome

A

glaucomatocyclitic crisis
affects one eye at a time
Young adults
Males
Recurrent episodes of acute, unilateral elevation of IOP associated with mild non-glanulomatous and non-painful uveitis
Possible viral infection? Allergic response?
Sx: high IOP (>45), white eye, ocular discomfort, blurred vision, cell/flare, corneal oedema, small KP
Treatment: IOP-lowering drops and steroids

19
Q

Ocular TB

A

Mycobacterium tuberculosis
Rare
Anterior uveitis, panuveitis, choroiditis
Choroidal lesions- severity of systemic disease TB and HIV

20
Q

Ocular Sarcoidosis

A

granulomatous disease affecting the lungs, skin, eyes
-conjunctival sarcoid, anterior, intermediate and posterior uveitis, panuveitis, choroidal nodules, ON involvement, lacrimal gland and extra-ocular muscles involvement.

21
Q

Toxoplasmosis

A

Toxoplasma gondii
Congenital transmission
May spontaneously reactivate
child may have-strabismus, nystagmus, low vision
Sx: none or blurred vision
Signs: inactive scar or active retinochoroiditis

22
Q

Syphilitic Uveitis

A

STI- caused by Treponema pallidum
Stages: primary, secondary and tertiary
Ophthalmic manifestation usually in the tertiary stage
Salt and pepper fundus RPE atrophy
Uveitis
Periphlebitis
Vasculitis Choroiditis Retinitis Papillitis Haemorrhages

23
Q

Sympathetic Ophthalmia

A

Bilateral granulomatous uveitis -history of eye trauma
10 days-years after the trauma
Cause: unknown. immune reaction against the patient’s uveal pigment??????
Inflamed first, then the other eye follows “sympathetically”

anti- inflammatory drugs