23/02 Flashcards
What are features of Autoimmune hepatitis?
Type 1- affects young women
ANA antibodies
Anti smooth muscle antibodies
IgG positive
What is the treatment of recurrent C diff infection?
Within 12wks of previous infection= fidaxomicin
>12 weeks post infection= vancomycin or fidaxomicin
How can IBS and IBD be differentiated in primary care?
Faecal calprotectin
What is the management of mild- moderate flare of UC?
Proctitis
- rectal mesalazine
- if no improvement within 4 wks then add oral
- if no improvement still then add oral prednisolone
Proctosigmoiditis and left sided UC
- topical mesalazine
- if remission not achieved then consider either stopping topical and adding oral mesalazine and topical steroid OR just add high dose oral mesalazine to topical
- if still no improvement then switch to oral mesalazine and prednisolone
Extensive disease
- oral and topical mesalazine
- if no improvement then stop topical treatment and add prednisolone
What is the management of a severe flare of UC?
IV steroids
If contraindicated then IV ciclosporin
If no improvement after 72hrs on IV steroid then add IV ciclosporin
How can the severity of C diff infection be determined?
By the WCC count
<15= moderate infection
>15= severe infection
Normal= mild infection
What are key features of achalasia?
Difficulty swallowing both solids and liquids- non progressive
Heartburn
Regurgitation
What is used first line to maintain remission in Crohns disease?
Azathioprine or mercaptopurine
What should be avoided in bowel obstruction?
Metoclopramide
What are causes of C diff infection?
Clindaymcin
Ceftriaxone
Cefotaxime
Cefuroxime
What is the best marker of acute liver failure?
Raised prothrombin time
Decreased albumin
What are features of Budd Chiari Syndrome?
Ascites
Abdo pain
Hepatomegaly
What are features of anaemia of chronic disease?
Total Iron Binding Capacity will be decreased
