2.3 Flashcards
(9 cards)
Nucleotide
Consists of a pentose sugar, phosphate group and nitrogenous base
Monomers of nucleic acids
Regulate metabolic pathways
May be components of coenzymes
DNA
Polynucleotide
Anti parallel
Covalent bond between sugar residue and phosphate group
Carry encoded info
Hydrogen bonding
Adenine and thymine double bond Guanine and cytosine triple bond - complimentary base pairing Double helix gives more stability Allow molecule to unzip for transcription and replication
How is DNA organised in cells
Nucleus
Looped DNA
DNA replicating
Self replicating
Takes place during interphase before the cell actually divides
Semi-conservative
- double helix unwinds catalysed by gyrase enzyme
-unzips as hydrogen bonds break catalysed by DNA helicase
-free nucleotides are bonded to exposed bases
-polymerase catalyses the addition of the new nucleotide bases
Mutations can occur
Transcription
The process of making mRNA from a DNA template
Gene unwinds and unzips Hydrogen bonds break RNA polymerase catalyses the formation of hydrogen bonds between RNA and DNA Complementary Out of NE to ribosome (Mg ions help)
Translation
Formation of a protein at ribosomes by assembling amino acids into a particular sequence
RNA
Ribose Uracil Single stranded Shorter Three forms
Genes
Length of DNA codes for polypeptide or length of RNA that is involved in regulating gene expression
Must be complimentary
Genetic code is near universal
Degenerate
Non-overlapping