Arthritis

Question 1

Contributing factor to osteoarthritis of the knee

Answer 1

obesity

Question 2

Symptoms seen with lumbar osteoarthritis

Answer 2

pain across low back/butt. LOM of flexion/extension

Question 3

Symptoms include progressive anterior shoulder pain that’s worse with motion. Difficulty with overhead activities, sleeping, axillary hygeine

Answer 3

osteoarthritis of shoulder

Question 4

Most common inflammatory arthritis

Answer 4

rheumatoid arthritis

Question 5

Characteristic joint deformities of the hands associated with rheumatoid arthritis

Answer 5

ulnar deviation at MP joints

Question 6

What is the term for gouty arthritis that affects the MP joint of the great toe?

Answer 6

podagra

Question 7

Finding in synovial fluid needed to make diagnosis of gout

Answer 7

urate crystals

Question 8

What is the term for pseudogout that occurs in soft tissues?

Answer 8

chondrocalcinosis

Question 9

Degeneration of cartilage leads to joint damage. Slowly hampers activities of daily living

Answer 9

osteoarthritis

Question 10

Autoimmune disease that attacks synovium and soft tissue. See swelling and damage/destruction of multiple joints

Answer 10

rheumatoid arthritis

Question 11

Deposition of crystals leads to joint inflammation and damage. Recurrent attacks, often the big toe

Answer 11

gout and pseudogout

Question 12

Bacterial infection of the joint. Medical emergency that needs surgery and IV antibiotics

Answer 12

septic arthritis

Question 13

Disease limited to the joint (one or several – more with age). Can see osteophyte formation, creaking with motion

Answer 13

osteoarthritis

Question 14

Generalized disease that results in multiple, swollen, painful joints. Usually starts in hands and feet and progresses proximally

Answer 14

rheumatoid arthritis

Question 15

Red, hot swollen joint / skin sensitivity. Can have multiple episodes that resolve over time

Answer 15

crystalline arthritis

Question 16

Red, hot, swollen joint / unable to bear weight or move freely. Constitutional symptoms

Answer 16

septic arthritis

Question 17

On imaging see joint space narrowing, osteophytes, subchondral sclerosis, subchondral cysts

Answer 17

osteoarthritis

Question 18

On imaging see joint space narrowing, bony erosions, soft tissue swelling, osteopenia about joint

Answer 18

rheumatoid arthritis

Question 19

On imaging can see joint destruction late in the course of the disease

Answer 19

gouty arthritis or infectious arthrititis

Question 20

Lab work results may include elevated ESR, CRP, anemia, leukocytosis, Rheumatoid factor and positive ACCP test

Answer 20

rheumatoid arthritis

Question 21

Lab work results may include elevated uric acid levels and crystals in joint fluid

Answer 21

gouty arthritis

Question 22

Lab work results may include elevated WBC w/left shift

Answer 22

septic arthritis

Question 23

Synovial fluid will be clear and negative for crystals

Answer 23

osteoarthritis

Question 24

synovial fluid will be slightly turbid with elevated WBC <25,000

Answer 24

rheumatoid arthritis

Question 25

synovial fluid will be turbid with either monosodium urate or calcium pyrophosphate dehydrate

Answer 25

crystalline arthritis

Question 26

synovial fluid will be turbid to purulent with positive gram stains and cultures

Answer 26

septic arthritis

Question 27

Treatment that has been shown to help knee pain

Answer 27

Intra-articular steroids and hyaluronans, Gentle exercises, Weight loss

Question 28

Gold standard treatment for severe knee, hip, or shoulder joint arthritis

Answer 28

total joint replacement

Question 29

Antimetabolite that inhibits purine biosynthesis which is essential to rapidly proliferating cells. Is the most commonly used DMARD

Answer 29

methotrexate

Question 30

Used for RA and psoriatic arthritis. Inhibits pyrimidine synthesis

Answer 30

Arava (Leflunomide)

Question 31

From human monoclonal antibody. Binds to tumor necrosis factor. Suppresses part of the immune system. expensive

Answer 31

humira (Adalimumab)

Question 32

Antibiotic treatment for gram positive septic arthritis

Answer 32

vanco

Question 33

Antibiotic treatment fro gram negative septic arthritis

Answer 33

3rd generation cephalosporin + macrolide