2.4 Flashcards

(26 cards)

1
Q

These surfaces may possess specialized structures such as microvilli, stereocilia, and cilia.

A

Apical Epithelial Surfaces

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2
Q

Apical Epithelial Surfaces

A
  • Microvilli
  • Stereocilia
  • Cilia
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3
Q
  • Microvilli
  • Stereocilia
  • Cilia
A

Apical Epithelial Surfaces

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4
Q

__________are fingerlike projections of epithelia approximately 1 _m long that extend into a lumen and increase the cell’s surface area.

A

Microvilli

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5
Q

Microvilli

A
  1. A glycocalyx (sugar coat) is present on their surfaces.
  2. A bundle of approximately 30 actin filaments runs longitudinally through the core of each microvillus and extends into the terminal web, a zone of intersecting filaments in the apical cytoplasm.
  3. Microvilli constitute the brush border of kidney proximal tubule cells and the striated border of intestinal absorptive cells.
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6
Q

Microvilli:

A ___________(sugar coat) is present on their surfaces

A

Glycocalyx

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7
Q

Microvilli:

A bundle of approximately ___________ runs longitudinally through the core of each microvillus and extends into the ___________________, a zone of intersecting filaments in the
apical cytoplasm

A

30 actin filaments; Terminal web

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8
Q

Microvilli:

A zone of intersecting filaments in the apical cytoplasm

A

Terminal web

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9
Q

Microvilli:

Microvilli constitute the brush border of _________ proximal tubule cells and the striated border of _________absorptive cells

A

Kidney; Intestinal

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10
Q

_____________are very long microvilli (not cilia) in the epididymis and vas deferens of the male reproductive tract.

A

Stereocilia

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11
Q

Stereocilia are very long microvilli (not cilia) in the __________ and _____________ of the male reproductive tract.

A

Epididymis; Vas deferens

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12
Q

_________ are actively motile processes 5 to 10 _m long extending from certain epithelia (e.g., tracheobronchial and oviduct epithelium) that propel substances along their surfaces. They contain a core of longitudinally arranged microtubules (the axoneme), which arises from a basal body during ciliogenesis.

A

Cilia

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13
Q

Cilia are actively motile processes ______ _m long extending from certain epithelia (e.g., tracheobronchial and oviduct epithelium) that propel substances along their surfaces. They contain a core of longitudinally arranged microtubules (the axoneme), which arises from a basal body during ____________.

A

5 to 10; Ciliogenesis

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14
Q

Cilia

A
  1. The axoneme consists of nine doublet microtubules uniformly spaced around two central microtubules (9 _ 2 configuration), as well as the following components:
    a. Ciliary dynein arms, which extend unidirectionally from one member of each doublet microtubule and interact with adjacent doublets, so that they slide past one another. These arms consist of ciliary dynein, with a head that is an ATPase that splits ATP to liberate the energy necessary for active movement of a cilium.
    b. Radial spokes that extend from each of the nine outer doublets toward the central sheath.
    c. Central sheath, which surrounds the two central microtubules; it and the radial spokes regulate the ciliary beat.
    d. Nexin, an elastic protein that connects adjacent doublet microtubules and helps maintain the shape of the cilium.
  2. The basal body is a cylindrical structure at the base of each cilium that consists of nine triplet microtubules arranged radially in the shape of a pinwheel (9 _ 0 configuration). It resembles a centriole but has a less complex central organization. The inner two triplets of the basal body give rise to the doublet microtubules of the cilium axoneme.
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15
Q

Cilia

A
  • Axoneme
  • Basal Body
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16
Q
  • Axoneme
  • Basal Body
17
Q

Cilia:

The _________ consists of nine doublet microtubules uniformly spaced around two central microtubules (9 _ 2 configuration)

18
Q

Cilia:

The axoneme consists of _____ doublet microtubules uniformly spaced around ____ central microtubules (9 _ 2 configuration)

19
Q

Axoneme

A
  • Ciliary dynein arms
  • Radial spokes
  • Central sheath
  • Nexin
20
Q
  • Ciliary dynein arms
  • Radial spokes
  • Central sheath
  • Nexin
A

Axoneme (Cilia)

21
Q

Cilia - Axoneme:

__________, which extend unidirectionally from one member of each doublet microtubule and interact with adjacent doublets, so that they slide past one another. These arms consist of ciliary dynein, with a head that is an ATPase that splits ATP to liberate the energy necessary for active movement of a cilium.

A

Ciliary dynein arms

22
Q

Cilia - Axoneme:

___________ that extend from each of the nine outer doublets toward the central sheath.

A

Radial spokes

23
Q

Cilia - Axoneme:

_____________ , which surrounds the two central microtubules; it and the radial spokes regulate the ciliary beat.

A

Central sheath

24
Q

Cilia - Axoneme:

________, an elastic protein that connects adjacent doublet microtubules and helps maintain the shape of the cilium.

25
The_____________ is a cylindrical structure at the base of each cilium that consists of nine triplet microtubules arranged radially in the shape of a pinwheel (9 _ 0 configuration). It resembles a centriole but has a less complex central organization. The inner two triplets of it give rise to the doublet microtubules of the cilium axoneme.
Basal body
26
The basal body is a cylindrical structure at the base of each cilium that consists of nine triplet microtubules arranged radially in the shape of a pinwheel (9 _ 0 configuration). It resembles a _________ but has a less complex central organization. The inner two triplets of the basal body give rise to the doublet microtubules of the cilium axoneme.
centriole