2.4 Flashcards
(26 cards)
These surfaces may possess specialized structures such as microvilli, stereocilia, and cilia.
Apical Epithelial Surfaces
Apical Epithelial Surfaces
- Microvilli
- Stereocilia
- Cilia
- Microvilli
- Stereocilia
- Cilia
Apical Epithelial Surfaces
__________are fingerlike projections of epithelia approximately 1 _m long that extend into a lumen and increase the cell’s surface area.
Microvilli
Microvilli
- A glycocalyx (sugar coat) is present on their surfaces.
- A bundle of approximately 30 actin filaments runs longitudinally through the core of each microvillus and extends into the terminal web, a zone of intersecting filaments in the apical cytoplasm.
- Microvilli constitute the brush border of kidney proximal tubule cells and the striated border of intestinal absorptive cells.
Microvilli:
A ___________(sugar coat) is present on their surfaces
Glycocalyx
Microvilli:
A bundle of approximately ___________ runs longitudinally through the core of each microvillus and extends into the ___________________, a zone of intersecting filaments in the
apical cytoplasm
30 actin filaments; Terminal web
Microvilli:
A zone of intersecting filaments in the apical cytoplasm
Terminal web
Microvilli:
Microvilli constitute the brush border of _________ proximal tubule cells and the striated border of _________absorptive cells
Kidney; Intestinal
_____________are very long microvilli (not cilia) in the epididymis and vas deferens of the male reproductive tract.
Stereocilia
Stereocilia are very long microvilli (not cilia) in the __________ and _____________ of the male reproductive tract.
Epididymis; Vas deferens
_________ are actively motile processes 5 to 10 _m long extending from certain epithelia (e.g., tracheobronchial and oviduct epithelium) that propel substances along their surfaces. They contain a core of longitudinally arranged microtubules (the axoneme), which arises from a basal body during ciliogenesis.
Cilia
Cilia are actively motile processes ______ _m long extending from certain epithelia (e.g., tracheobronchial and oviduct epithelium) that propel substances along their surfaces. They contain a core of longitudinally arranged microtubules (the axoneme), which arises from a basal body during ____________.
5 to 10; Ciliogenesis
Cilia
- The axoneme consists of nine doublet microtubules uniformly spaced around two central microtubules (9 _ 2 configuration), as well as the following components:
a. Ciliary dynein arms, which extend unidirectionally from one member of each doublet microtubule and interact with adjacent doublets, so that they slide past one another. These arms consist of ciliary dynein, with a head that is an ATPase that splits ATP to liberate the energy necessary for active movement of a cilium.
b. Radial spokes that extend from each of the nine outer doublets toward the central sheath.
c. Central sheath, which surrounds the two central microtubules; it and the radial spokes regulate the ciliary beat.
d. Nexin, an elastic protein that connects adjacent doublet microtubules and helps maintain the shape of the cilium. - The basal body is a cylindrical structure at the base of each cilium that consists of nine triplet microtubules arranged radially in the shape of a pinwheel (9 _ 0 configuration). It resembles a centriole but has a less complex central organization. The inner two triplets of the basal body give rise to the doublet microtubules of the cilium axoneme.
Cilia
- Axoneme
- Basal Body
- Axoneme
- Basal Body
Cilia
Cilia:
The _________ consists of nine doublet microtubules uniformly spaced around two central microtubules (9 _ 2 configuration)
Axoneme
Cilia:
The axoneme consists of _____ doublet microtubules uniformly spaced around ____ central microtubules (9 _ 2 configuration)
9; 2
Axoneme
- Ciliary dynein arms
- Radial spokes
- Central sheath
- Nexin
- Ciliary dynein arms
- Radial spokes
- Central sheath
- Nexin
Axoneme (Cilia)
Cilia - Axoneme:
__________, which extend unidirectionally from one member of each doublet microtubule and interact with adjacent doublets, so that they slide past one another. These arms consist of ciliary dynein, with a head that is an ATPase that splits ATP to liberate the energy necessary for active movement of a cilium.
Ciliary dynein arms
Cilia - Axoneme:
___________ that extend from each of the nine outer doublets toward the central sheath.
Radial spokes
Cilia - Axoneme:
_____________ , which surrounds the two central microtubules; it and the radial spokes regulate the ciliary beat.
Central sheath
Cilia - Axoneme:
________, an elastic protein that connects adjacent doublet microtubules and helps maintain the shape of the cilium.
Nexin