2.4 eukaryotic cell structure Flashcards

1
Q

What is metabolism?

A

Involved both the synthesis and the breaking down of molecules.

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2
Q

What do chemical reactions in cells require?

A

Enzymes and specific reaction conditions

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3
Q

What does the nucleus do?

A

Contains coded genetic information in the form of DNA molecules. DNA directs the synthesis of all proteins required by the cell. So the DNA controls the metabolic activities of the cell, as many of these proteins are the enzymes necessary for metabolism to take place.

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4
Q

Size of nucleus

A

Often the biggest single organelle in the cell

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5
Q

Structure of the nucleus

A

DNA is contained within a double membrane called the nuclear envelope to protect it from damage in the cytoplasm. The nuclear envelope contains nuclear pores that allow molecules to move into and out of the nucleus (e.g. smaller RNA molecules).

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6
Q

What is chromatin?

A

DNA associates with proteins called histones to form a complex called chromatin. Chromatin coils and condenses to form structures known as chromosomes. These only become visible when cells are preparing to divide.

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7
Q

What is the nucleolus?

A

An area within the nucleus + is responsible for producing ribosomes. Composed of proteins and RNA. RNA is used to produce ribosomal RNA (rRNA) which is then combined with proteins to form the ribosomes necessary for protein synthesis.

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8
Q

What are mitochondria?

A

The site of the final stages of cellular respiration, where the energy stored in the bonds complex, organic molecules is made available for the cell to use by the production of ATP.

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9
Q

Correlation between mitochondria and energy

A

The more numbers of mitochondria in a cell, the more energy it is likely to use so is more active.

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10
Q

Structure of mitochondria

A

Mitochondria have a double membrane. Inner membrane is highly folded to form structures called cristae + the fluid interior is called the matrix. The membrane forming the cristae contains enzymes used in aerobic respiration.

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11
Q

What else do mitochondria contain?

A

A small amount of DNA called mitochondrial (mt) DNA. Mitochondria can produce their own enzymes and reproduce themselves.

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12
Q

What are vesicles?

A

Membranous sacs that have storage and transparent roles. They consist simply of a single membrane with fluid inside. Vesicles are used to transport materials inside the cell.

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13
Q

What are lysosomes?

A

Specialised forms of vesicles that contain hydrologic enzymes.

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14
Q

What is the role of lysosomes?

A

Responsible for breaking down waste material in cells, including old organelles. Important to the immune system as they break down pathogens ingested by phagocytic cells. Also play a role in programmed cell death or apoptosis.

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15
Q

What is the cytoskeleton?

A

A network of fibres necessary for the shape and stability of a cell. Organelles are held in place by the cytoskeleton + it controls cell movement + the movement of organelles within cells.

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16
Q

What are the cytoskeleton 3 components?

A

Microfilaments, microtubules, intermediate fibres.

17
Q

What are microfilaments?

A

Contractile fibres formed from the protein actin. Responsible for cell movement and also cell contraction during cytokinesis.

18
Q

What are microtubules?

A

Globular tubulin proteins polymerise to form tubes that are used to form a scaffold-like structure that determines the shape of a cell. Act as tracks for the movement of organelles, including vesicles, around the cell. Spindle fibres are composed of microtubules.

19
Q

What are intermediate fibres?

A

These fibres give mechanical strength to cells + help maintain their integrity.

20
Q

What are centrioles?

A

A component of the cytoskeleton present in most eukaryotic cells except flowering plants + most fungi. Composed of microtubules. 2 associated centrioles form the centrosome. Play a role in the positioning of the flagella and cilia.

21
Q

What is the centrosome involved in?

A

The centrosome is involved in the assembly and organisation of the spindle fibres during cell division.

22
Q

What are flagella?

A

Whip-like extensions that protrude from some cell types. Longer (than cilia).

23
Q

What are flagella used for?

A

Primarily used to enable cells motility. Some cells they are used as a sensory organelle detecting chemical changes in the cells environment.

24
Q

What are cilia?

A

Hair-like extensions that protrude from some cell types. Usually present in much greater numbers than flagella. Can be mobile or stationary.

25
Q

What is the role of stationary cilia?

A

Stationary cilia are present on the surface of many cells + have an important function in sensory organs like the nose.

26
Q

What is the role of mobile cilia?

A

Mobile cilia beat in a rhythmic manner, creating a current, and cause fluids or objects adjacent to the cell to move (e.g. in trachea and in Fallopian tubes).

27
Q

What is the key function of a cell?

A

To synthesis proteins for internal use and for secretion (transport out of the cell).

28
Q

What organelles are required for protein synthesis?

A

Ribosomes, the endoplasmic reticulum, the Golgi apparatus and the cytoskeleton.

29
Q

What is the endoplasmic reticulum?

A

The ER is a network of membranes enclosing flattened save called cisternae. It is connected to the outer membrane of the nucleus.

30
Q

What are the 2 types of ER?

A

Smooth ER and Rough ER

31
Q

What is smooth ER responsible for?

A

Smooth endoplasmic reticulum is responsible for lipid and carbohydrate synthesis, and storage.

32
Q

What is rough ER responsible for?

A

Rough endoplasmic reticulum has ribosomes bound to the surface and is responsible for the synthesis and transport of proteins.

33
Q

Which cells have more rough ER?

A

Secretary cells since they release hormones or enzymes (proteins).

34
Q

What are ribosomes?

A

The site of protein synthesis. Can be free-floating in cytoplasm or attached to ER making it rough ER.

35
Q

Structure of ribosomes

A

Not surrounded by a membrane. Constructed of RNA molecules made in the nucleoulus of the cell.

36
Q

What is the role of the Golgi apparatus?

A

It has a role in modifying proteins and ‘packagng’ them into vesicles. These may be secretory vesicles if the proteins are destined to leave the cell, or lysosomes which stay in the cell.

37
Q

Structure of Golgi apparatus

A

Similar in structure to the smooth ER. Compact structure formed of cisternae and does not contain ribosomes.

38
Q

Describe protein production (1-3)

A
  1. Proteins are synthesised on the ribosomes bound to the ER.
  2. They then pass into its cisternae and are packaged into transport vesicles
  3. Vesicles containing the newly synthesised proteins move towards the Golgi apparatus via the transport function of the cytoskeleton.
39
Q

Describe protein production (4-5)

A
  1. The vesicles fuse with the cis face of the Golgi apparatus + proteins enter. The proteins are structurally modified before leaving the GA in vesicles from its trans face.
  2. Secretory vesicles carry proteins that are to be released from the cell. The vesicles move towards and fuse with the cell-surface membrane, releasing their contents by exocytosis. Some vesicles from lysosomes - these contain enzymes for use in the cell.