Nucleic Acids Flashcards

1
Q

Trimethoprim

A

Dihydrofolate reductase

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2
Q

Sulfamethoxazole

A

Dihydropteroate synthase

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3
Q

Initiation of translocation in prokaryotes

A

Shine-Delgano sequence

Purine-rich

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4
Q

SCID

A

Adenosine deaminase

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5
Q

Common precursors of purines and pyrimidines

A

CO2
Glutamate
Aspartic acid

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6
Q

purine and pyrimidine are deoxygenated at carbon _

A

C2

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7
Q

true or false: glycine and folate are used in pyrimidine synthesis

A

false

only aspartic acid, glutamine and CO2

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8
Q

true or false: glutamate donates atoms to purine and pyrimidine

A

glutamINE

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9
Q

true or false: N5-folate donates atoms to purine and pyrimidine

A

N10-folate

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10
Q

true or false: Lesch-Nayhan syndrome is associated with guanosine

A

guaNINE

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11
Q

true or false: in SCID, there is inhibition of ADA

A

defect of ADA

inhibition of ribonucleotide reductase

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