SAQ 4

Question 1

1. GFR results in large quantities of _____________ in plasma (180 L/day)

Answer 1

Ultrafiltrate

Question 2

most of the process of reabsorption occurs in the _________ _______ (60%)

Answer 2

Proximal Tubule

Question 3

sodium and chloride are reabsorbed from the filtrate in the __________ ______ in the loop of henle. the reabsorption of salt makes the tubule fluid dilute which creates and maintains a high osmotic pressure in the ______ interstitial fluid.

Answer 3

ascending Limb

Medullary

Question 4

Late distal and cortical collecting tubules contain _______ _____ which secrete K ions and reabsorbs Na

Answer 4

Principal cells

Question 5

Late distal and cortical collecting tubules also contain _______ _____ which secretes H

Answer 5

intercalated cells

Question 6

Decreased Na reabsorption and decreased K secretion, lack of aldosterone = ________ ________

Answer 6

Addisons Disease

Question 7

_________ _______= decreased Na, Ca, HCO3 reabsorption, hypotension, decreased activity of Na‐K‐2 Cl transporter in loop of Henle

Answer 7

Bartter’s syndrome

Question 8

_____________ ____________: decreased NaCl reabsorption, hypotension, decreased activity of NaCl cotransporter in distal tubule.

Answer 8

Gitleman’s syndrome

Question 9

__________ ______________: generalized decreae in reabsorption often in
proximal tubules. (Genetics, heavy mental damage, drugs, multiple myeloma, tubular necrosis)

Answer 9

Fanconi syndrome

Question 10

_________ ________ _________= decreased H secretion, increased HCO3 excretion, acidosis (genetic, renal injury, etc)

Answer 10

Renal tubular acidosis