Atypical antipsychotics Flashcards

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1
Q

Atypical antipsychotics

A
Olanzapine
Clozapine
Quetiapine
Risperidone
Aripiprazole
Ziprasidone

“It is atypical for OLd CLOSets to QUIETly RISPER from A to Z”

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2
Q

MOA

A

Not understood

Varied effect on 5HT2, dopamine, and alpha and H1 receptor

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3
Q

Clinical use

A

Schizophrenia: both positive AND NEGATIVE symptoms (vs. antipsychotics)

Bipolar,
OCD
Anxiety disorder
Depression,
Mania,
Tourette's (associated with OCD)
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4
Q

Toxicity

A

Fewer EPS and anticholinergic than traditional antipsychotic.

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5
Q

Olanzapine and clozapine

A

Weight gain

“Oil and Carb make you FAT”

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6
Q

Clozapine

A

agranulocytosis (weely WBC)

Seizure

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7
Q

Ziprasidone

A

PRolong GT

ziPRasidone

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