Tumour Markers

Question 0

Calcitonin

Answer 0

Relevant: medullary thyroid
Associated: none
Other: thyroid c- cell hyperplasia

Question 1

Alpha fetoprotein

Answer 1

Relevant: testicular, hepatocellular
Associated: colorectal, gastric, hepatobillary, lung
Other: cirrhosis, pregnancy, neural tube defects

Question 2

CA-125

Answer 2

Relevant: ovarian
Associated: breast, cervical, endometrial, hepatocellular, lung, non-Hodgkin, pancreatic, medullary thyroid, peritoneal, uterine
Other: many!! CF, diabetes, pregnancy, HF, rheum, endometriosis ETC

Question 3

CA 19-9

Answer 3

Relevant: pancreas
Associated: colorectal, gastric, hepatocellular, oesophageal, ovarian
Other: cholangitis/cholestasis, pancreatitis, diabetes

Question 4

CA 15-3

Answer 4

Relevant: breast (monitoring treatment and recurrence)
Associated: hepatocellular, pancreatic
Other: cirrhosis, can be found in normal health

Question 5

Carcinoembryonic antigen (CEA)

Answer 5

Relevant: colorectal
Associated: breast, gastric, lung, mesothelioma, oesophageal, pancreatic
Other: smokers, chronic liver/ kidney disease, diverticulitis, jaundice

Question 6

Beta Human chorionic gonadotrophin (in oncology)

Answer 6

Relevant: testicular, gestational trophoblastic
Associated: lung
Other: preggers obvs

Question 7

Paraproteins

Answer 7

Relevant: B cell proliferative
Associated: none
Other: none

Question 8

Thyroglobulin

Answer 8

Relevant: thyroid (follicular/papillary)
Associated: none
Other: none