27. Insulin and Glucagon Flashcards

1
Q

two polypeptide chains with 51 amino acids

linked by 2 disulfide bridges

A

insulin

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2
Q

singly polypeptide with 29 amino acids

A

glucagon

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3
Q

second messenger of

insulin

A

tyrosine kinase

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4
Q

second messenger of

glucagon

A

cAMP

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5
Q

stimulus for secretion of glucagon

A

actual or potential hypoglycemia

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6
Q

stimulus for secretion

of insulin

A
  • ingestion of glucose and amino acids
  • cholecystokinin and
  • gastric inhibitory peptide
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7
Q

pathways
increased

insulin

A

glucose uptake
glycogenesis
protein synthesis
lipogenesis

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8
Q

pathways
increased

glucagon

A
gluconeogenesis 
glycogenolysis 
uptake of amino acids 
beta oxidation
ketogenesis
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9
Q

pathways
decreased

insulin

A

gluconeogenesis
glycogenolysis
beta oxidation

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10
Q

pathways
decreased

glucagon

A

glycogenesis

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11
Q

chemicals with similar effect with glucagon

A

epinephrine
cortisol
growth hormone

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