UW 12 Flashcards

1
Q

AE’s of Lithium

A
GI distress
Nephrotoxic
Hypothyroidism
Leukocytosis
Tremors
Acne
Psoriasis flares
Hair loss
Edema
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2
Q

MCC death Dialysis

A

Cardiovascular

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3
Q

Nerve that does knee extension and hip flexion

A

Femoral Nerve

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4
Q

Provides sensation to anterior thigh and medial leg

A

Femoral Nerve

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5
Q

Adduction of leg and sensation of medial thigh

A

Obturator Nerve

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6
Q

Tx of infertility for premature ovarian failure

A

IVF w donor oocyte only option

No viable oocytes

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7
Q

Cardiac amyloidosis

A

Unexplained CHF
Echo = increased LV thickness, normal LV cavity
Low voltage EKG

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8
Q

Amyloidosis Pathophys

A

Extracellular deposit of insoluable polymeric protein fibrils in tissues and organs

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9
Q

Amyloidosis secondary due to?

A
Inflammatory arthritis 
Chronic Infxn
IBD
Malignancy
Vasculitis
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10
Q

Amyloidosis Presentation

A
Asymptom proteinuria 
Nephrotic syndrome
Hepatomegaly
Peripheral Neuropathy
Visible organ enlargement
Bleeding diathesis
Waxy thickening, skin bruising
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11
Q

Dx for Amyloidosis

A

Tissue Bx

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12
Q

What is a torus palatinus

A
Growth on hard palate
Fleshy, immobile mass
Benign
Midline suture 
Genetic and environmental
Ulcerates w trauma 
Heals slowly
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13
Q

Tx for torus palatinus

A

Surgery

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14
Q

What does aromatase do

A

Converts androgens into estrogens

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15
Q

Presentation of aromatase deficiency

A
Masculinization of mother resolves w delivery
Virilization
Normal internal genitalia
Ambigious external genitalia
Clitoromegaly
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16
Q

Presentation of aromatase deficiency later in life

A

Delayed puberty
osteopororosis
Undetectable estrogen
Polycystic ovaries

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17
Q

Labs with aromatase deficiency

A

High FSH/LH

Low estrogen

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18
Q

McCune Albright triad

A

Cafe au lait spots
Polyostotic fibrous dysplasia
Autonomous endocrine hyperfnc
- Precocious puberty

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19
Q

Kallman syndrome Presentation and Labs

A
46 XX
Hypogonadotropic hypogonadism
Anosmia
Delayed puberty
Normal internal reproductive organs
Low or absent LH and FSH
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20
Q

Tx for premature ovarian failure infertility

A

IVF with donor oocytes

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21
Q

Premature ovarian failure

A
< 40 yoa
Amenorrhea
Hypoestrogenism
Increased FSH and LH
Low Estrogen
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22
Q

Management for threatened abortion

A

Reassurance and outpatient f/u after assess fetus w US

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23
Q

Tx for asymptomatic PVCs

A

Observation

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24
Q

Tx for symptomatic PVCs

A

Beta blockers

Amiodarone

25
Q

Langerhans cell histiocytosis Presentation

A

Solitary, lytic long bone lesion
Painful, tender swelling
Hypercalcemia

26
Q

Tx for HCV

A

Peg IFN

Ribavarin

27
Q

Anticholinergic excess si/sx’s

A

Red as a beet - flushing
Dry as a bone - anhidrosis/dry mouth
Hot as a hare - hyperthermia
Blind as a bat - vision changes/mydriasis
Mad as a hatter - delirium/confusion
Full as a flask - urinary retention/constipation

28
Q

Parkinson drug with anticholinergic excess sx’s

A

Trihexyphenidyl

Benztropine

29
Q

Presentation of amebic liver abscess

A
Hx of travel
Dystentery
RUQ pain
Single cyst - right lob of liver
Bloody diarrhea
Pleuritic like pain - if on surface
30
Q

Dx for E.Histolytica infxn

A

Stool for trophozoities
Serology
Liver imaging

31
Q

Hydatid cyst

A

Echinococcus granulosos

Dog contact

32
Q

Hepatic adenoma

A

Solid lesion

33
Q

What is another name for pseudotumor cerebri

A

Idiopathic intracranial HTN

IIH

34
Q

Meds that cause IIH

A

Vit A and derivatives
GH
Tetracyclines

35
Q

MEN Type I

A

Primary PTH
Enteropancreatic tumors
Pituitary tumors

36
Q

MEN 2A

A

Medullary thyroid cancer
Phaeo
Parathyroid hyperplasia

37
Q

MEN 2B

A

1.MTC
2. Pheo
3.Mucosal/intestinal neuromas
Marfanoid

38
Q

Extra renal complications of ADPKD

A
  1. Hepatic cysts
  2. Valvular heart dz - MVP, AR
  3. Colonic diverticula
  4. Abd wall and inguinal hernia
39
Q

Isolated Systolic HTN (ISH) Pathophysiology

A

Decreased elasticity of arterial wall -> increased SBP (no change in DBP)
Rigid arteries with aging = reduces compliance, and ability to dampen SBP

40
Q

Tx for ISH

A

Low dose thiazide
ACE
CCB - long acting

41
Q

What is PANDAS

A

Pediatric AI Neuropsychiatric disorder

42
Q

How does PANDAS present

A

Recent GAS infxn
Acute onset OCD
Tic disorder

43
Q

What heart change seen in cor pulmonale

A

TR
Loud P2
RV S3

44
Q

Dx with cath for cor pulmonale

A

Elevated PA SBP

> 25 mmHg

45
Q

What does PCWP estimate

A

LV EDV

46
Q

What is presentation of Necrolytic Migratory Erythema (NME)

A

Erythematous papules/plaques
Coalesce
Form large, painful, inflammatory blisters
+/- crusting and central clearing

47
Q

Presentation of glucagonoma

A
DM
NME
Wt loss
Diarrhea
Anemia
48
Q

Glucagonoma v Gastrinoma

A

Both: diarrhea, wt loss, anemia, abd pain

Only glucagonoma ass’d with DM and NME

49
Q

How to confirm dx of glucagonoma?

A

Glucagon > 500 pg/mL

50
Q

NPV relationship with pretest probability

A

Pt with high probability of having dz = LOW NPV

Pt with low probability of having dz = HIGH NPV

51
Q

Do sensitivity and specificity vary with pretest probability

A

NO

52
Q

What measures probability of being free of dz if test result is negative

A

NPV

53
Q

Management of DM pt w acute pyelonephritis

A

Parenteral Abx 48-72 hrs

Clear response - change to oral abx for 10-14 days

54
Q

What is the Ghon complex

A

Tubercle
Ass’d LA
Reactivation TB = upper lobe infiltrate

55
Q

Comorbidities of panic disorder

A
Major Depression
Bipolar
Agoraphobia
Substance Abuse
Increased SI/attempts
56
Q

Disorders ass’d with Vitiligo

A
Pernicious Anemia
Grave's
Type 1 DM
Primary adrenal insufficiency
Hypopituitarism
Alopecia areata
57
Q

Where do we see pleural plaques

A

Bronchogenic carcinoma

58
Q

What is the MC malignancy ass’d with asbestos

A

Bronchogenic Carcinoma

then, mesothelioma

59
Q

What vitamin reduces morbidity and mortality in measles

A

Vit A