Acid Base Flashcards

1
Q

The water content of an average adult male contains ___% water

A

61

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2
Q

The average adult female contains ___% water

A

50

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3
Q

Is sodium concentration higher in intercellular or extracellular fluid?

A

Extracellular

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4
Q

Where does water move if the solute concentration in the extracellular fluid decreases?

A

Into the cell

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5
Q

The dominant extracellular cations are

A

Sodium (Na+)

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6
Q

Large organic molecules such as proteins are usually found in the

A

Intracellular fluid & Plasma

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7
Q

Abnormal stretching of vessels due to increased blood pressure stimulates the release of

A

Atrial natriuretic hormone

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8
Q

The most important regulator of blood osmolality is

A

ADH

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9
Q

If blood pressure decreases, blood levels of ____ increase

A

aldosterone, angiotensin II, ADH, renin

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10
Q

Which ions are the most important for establishing the resting membrane potential

A

Potassium (K+)

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11
Q

____plays a major role in regulating the concentration of K+ ion secretion in the distal tubule and collecting duct.

A

Aldosterone

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12
Q

Aldosterone secretion from the adrenal cortex is stimulated by the renin-angiotensin system and

A

elevated blood K+ ion levels

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13
Q

____ is necessary for the transport of Ca2+ ions across the wall of the intestinal tract

A

Vitamin D

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14
Q

Hypocalcemia has which symptom?

A

Muscle spasms

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15
Q

The major mechanism that controls plasma levels of calcium ions is

A

parathyroid hormone secretion

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16
Q

The most abundant negatively charged ion in the extracellular fluid is

A

chloride

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17
Q

Loss of a large volume of sweat results in the body fluids becoming _____ which causes _____ in plasma volume

A

hypertonic, a decrease

18
Q

Thirst is stimulated by

A

increased osmolality of the blood, decreased blood volume, increased angiotensin II

19
Q

During conditions of severe dehydration, hematocrit _____, which results in an_____ in blood viscosity

A

Increase, increase

20
Q

What is the primary organ that regulates the composition and volume of body fluids

A

Kidneys

21
Q

Which of these conditions produces a large volume of dilute urine?

A

Decreased ADH secretion

22
Q

What is not a major buffer system in the body

A

lactic acid buffer system

23
Q

What do buffers do?

A

bind to excess H+ ions that are added to a solution.
Prevent large changes in body fluid pH.
May involve weak acids
Release H+ ions when H+ ion concentration in a solution falls

24
Q

Nephrons directly regulate acid-base balance by

A

secreting H+ ions into the filtrate

25
Q

The major effect of acidosis is the ____ of the nervous system, whereas a major effect of alkalosis is _____ of the nervous system

A

depression, hyperexcitability

26
Q

Respiratory regulation of pH depends upon the

A

carbonic acid/bicarbonate buffer system

27
Q

The largest buffer system in the body is the

A

Protein buffer system

28
Q

Potassium imbalances infrequently occur, they are the most dangerous. In looking at an EKG what will be seen?

A

U wave and flattened T wave with low K+

Tall, tented T wave in high K+

29
Q

The inability to eliminate CO2 from the body causes pH to ____ and can result in _____

A

decrease, acidosis

30
Q

Increased ammonia in the urine may indicate

A

respiratory acidosis

31
Q

Respiratory alkalosis can be caused by

A

hyperventilation

32
Q

Sedatives or opioid overuse can cause

A

respiratory acidosis

33
Q

What are some conditions that would cause fluid imbalance of hypervolemia?

A

Ingesting large amounts of water, injection of hypotonic solution, endocrine d/o such as excessive ADH production, lymphedema

34
Q

What clinical assessment would you find with hypervolemia?

A

Elevated BP, edema, prominent JVD, hemodilution, dyspnea, crackles, weight gain, low NA levels, CNS effects, bounding pulse

35
Q

What are some conditions that may cause hypovolemia?

A

Inadequate fluid intake, hemorrhage, fever, repeated vomiting, diarrhea

36
Q

What clinical assessment would you find with hypovolemia

A

Loss of one or more electrolyte, thirst, hemoconcentration, high urine specific gravity, high serum electrolyte levels.

37
Q

A patient with a positive Chvostek’s sign would more than likely receive IV administration of

A

Calcium gluconate

38
Q

Diabetes insipidius causes

A

hypernatremia

39
Q

Vitamin D deficiency causes

A

hypocalcemia

40
Q

Metabolic alkalosis causes

A

hypokalemia

41
Q

Crushing injury causes

A

hyperkalemia

42
Q

SIADH causes

A

hyponatremia