29 Flashcards

(56 cards)

1
Q

4 steps of food processing

A

Ingestion, digestion, absorption, egestion

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2
Q

Mouth function

A

Does physical digestion (bigger to smaller pieces) & chemical digestion (chemical bonds broken. Ex. Saliva’s enzymes)

Saliva has enzyme called amylase which digests starch. It also has mucus, which lubricates & helps with swallowing.

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3
Q

Esophagus

A

Epiglottis is a small flap of tissue that closes over trachea when swallowing. Bolus (the shape) of food moves down from esophagus to stomach due to peristalsis (wave-like contractions).

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4
Q

Stomach - Sphincters

A

Sphincters are circular muscles that control movement of food in & out of stomach.

Gastroesophageal sphincter controls entry of food, while pyloric sphincter controls the exit of food.

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5
Q

Stomach - Layers

A

Mucosa - innermost layer made of epithelial cells that secretes gastric juice (which has enzymes, acid, & mucus)

Muscle layer - breaks down food by contracting frequently, forming chyme (semi-liquid mixture of food & gastric juice). This soupy liquid enters the small intestine.

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6
Q

Stomach - Gastrin (mucus, HCI, pepsin)

A

Gastrin (hormone) helps release gastric juice from mucosa cells. Mucus coats & protects stomach lining. Hydrochloric acid (pH 2-3) kills bacteria & activates enzyme pepsin (from inactive pepsinogen), which digests proteins.

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7
Q

Small intestines - Size and what parts? Also what is its purpose?

A

2.5cm in diameter, up to 7m in length.

Parts

Duodenum - first 25-30cm; for digestion

Jejunum - digestion & some absorption

Ileum - absorption

The small intestine breaks down food and absorbs nutrients.

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8
Q

Small intestine - Inner surface (Villi, microvilli, lacteals)

A

Inner layers are folded into ridges. They have smaller folds/finger-like projections called villi. The villi have even smaller, microscopic projections called microvilli.

Nutrients go from mucosa in small intestine into capillary networks in villi.

These villi have network of capillaries that pick up absorbed nutrients (except digested fats). The fats are transported (absorbed) through small vessels called lacteals.

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9
Q

Chemical Digestion in Small Intestine (Duodenum) (Chyme > Prosecretin, Secretin, CCK)

A

Acidic chyme enters duodenum (through pyloric sphincter), and epithelial cells convert prosecretin to secretin. Fat in chyme causes the release of hormone CCK (cholecystokinin).

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10
Q

Role of Pancreas in Small Intestine - The hormones & enzymes they release (HCO3- ions, trypsinogen, trypsin, enterokinase, lipases)

A

Secretin (hormone) stimulates pancreas to release HCO3- (bicarbonate ions). These ions have a pH of 9, which inactivates the pepsin in chyme. The ions travel from pancreas to pancreatic duct and then into duodenum.

The hormone CCK (from duodenum) releases pancreatic juice (containing digestive enzymes & HCO3- ions) that signals the stomach to slow down digestion.

Pancreas also releases trypsinogen, which activates into trypsin (enzyme, after travelling from pancreas into duodenum, helps digest protein) by enzyme enterokinase.

It also releases lipases (enzyme), which help break down lipids (fats). Digested fats are absorbed through lacteals.

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11
Q

Role of Liver and Gall Bladder in Small Intestine

A

The liver creates bile which is stored in the gall bladder. Bile is a substance that emulsifies (breaks) fat down into smaller pieces (physical digestion).

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12
Q

Absorption in Small Intestine

A

In jejunum & ileum, through…

Passive transport - movement of materials across a cell membrane without use of energy. Uses osmosis (movement of water from area with more water to area with less water) and facilitated diffusion (diffusion of molecules across membrane through transport proteins). Moves materials down concentration gradient.

Active transport - movement of materials across a cell membrane with use of energy. Moves materials up concentration gradient.

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13
Q

Large intestine - Size and what parts? Also what is its purpose?

A

7.6cm in diameter, 1.5m in length. Cecum (with appendix) is the start of the large intestine, and is a pouch that receives material from small intestine.

Colon has 4 segments, and is the longest part.

There is also the rectum (last 20cm of large intestine) and the anus (the external opening).

The large intestine absorbs water & produces essential vitamins.

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14
Q

Egestion - What happens? Also, what is the role of dietary fiber in human egestion?

A

Rectum holds waste until eliminated as feces through anus.

Dietary fiber helps prevent/relieve constipation.

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15
Q

What are the 4 components of the digestive process?

A

ingestion, digestion, absorption, egestion

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16
Q

What enzyme is present in saliva? What nutrient does it digest?

A

amylase; It starts the digestion of starch (a carbohydrate).

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17
Q

What is the food called as it leaves the mouth? as it leaves the stomach?

A

bolus; chyme

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18
Q

In the human gastrointestinal tract, physical (mechanical) digestion of nutrients occurs in 2 different locations. Describe what happens in each of these locations.

A

-mouth: teeth chew food

-stomach: muscles contract frequently to break apart food

(Could also add small intestine, but it only applies to lipids: bile emulsifies fat)

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19
Q

What causes the food to move down the esophagus?

A

peristalsis (rhythmic contractions of muscles)

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20
Q

What 2 structures increase the internal surface area of the small intestine by 500 times?

A

(folds &) villi, microvilli

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21
Q

Name all of the organs that food passes through (in order) in the human digestive system, starting with the mouth.

A

mouth, esophagus, stomach, small intestine, large intestine, anus

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22
Q

Name 3 accessory organs to the digestive system.

A

any 3 of: liver, pancreas, gall bladder, salivary glands

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23
Q

Name the 2 muscles that allow food into and out of the stomach.

A

gastroesophageal sphincter & pyloric sphincter

24
Q

What are the 3 components of the gastric juice in the stomach and what do they do?

A

mucus: protects the lining of the stomach from acid & enzymes

hydrochloric acid: kills pathogens, activates pepsinogen

pepsinogen: when activated (to pepsin), it digests proteins

25
Name 2 hormones secreted by the cells of the duodenum.
secretin (it signals the liver + pancreas) & cholecystokinin (CCK) (signals the pancreas + stomach)
26
The presence of acid in the duodenum (small intestine) causes a chemical signal to be sent to the pancreas. What does the pancreas release that neutralizes the acid?
bicarbonate ions
27
Name 3 digestive enzymes that are secreted into the duodenum.
Any 3 of: -enterokinase (converts trypsinogen to trypsin) -trypsin (digests proteins) -lipase (breaks down fats) -amylase (digests starch) -carboxypeptidase -erepsins (digests proteins)
28
What is 1 main function of the large intestine?
Any 1 of: water absorption; vitamin & ion absorption; home to important bacteria
29
What are the 3 sections of the small intestine? What part of the digestive process occurs only in the last 2 sections?
duodenum, jejunum & ileum; absorption of nutrients occurs here
30
Where is bile produced, and where is it stored?
bile is produced in the liver, stored in the gall bladder
31
Diaphragm, external/internal intercostal muscles, pleural membranes
Diaphragm - large sheet of muscle located beneath lungs that is the primary muscle in breathing External intercostal muscles - for normal breathing - muscles that raises ribcage, decreasing pressure in chest cavity Internal intercostal muscles - for strenuous exercise or forced exhalation - muscle that pulls ribcage downward, increasing pressure in chest cavity Pleural membranes - Protective 2 layers surrounding the lungs
32
Ventilation and what does diaphragm & external/internal intercostal muscles do during ventilation
Ventilation - process of getting air to the respiratory system Diaphragm, external & internal intercostal muscles change the volume & pressure in the chest cavity. Air moves from high to low pressure.
33
Lung capacity diagram terms...
Total lung capacity: Maximum volume of air that can be inhaled Tidal volume: Volume of air inhaled or exhaled during a normal, involuntary breath. In average adult = 0.5 L Inspiratory reserve volume: Volume of air that can be forcibly inhaled after a normal inhalation. Expiratory reserve volume: Volume of air that can be forcibly exhaled after a normal exhalation. Residual volume: Volume of air remaining in lungs after a forced exhalation Vital capacity: Maximum amount of air that can be inhaled or exhaled
34
Function of hemoglobin
Hemoglobin is the protein that carries 98.5% of the oxygen in our blood cells. The other 1.5% is dissolved in the liquid part of the blood. Oxygen diffuses from alveoli into liquid part of blood & blood cells. Hemoglobin increases blood's capacity to carry oxygen by nearly 70 times as without it! It also binds with molecules of oxygen to form oxyhemoglobin, which gives oxygenated blood its bright red colour (deoxygenated is dark red)
35
How O2 and CO2 are carried in blood
Oxygen: Diffuses from alveoli into blood plasma and then into blood cells Carbon dioxide: 73% forms carbonic acid, 20% attaches to hemoglobin, 7% dissolved in plasma
36
How do pressure & volume affect inhalation?
When you inhale, the volume of the chest cavity is increased & the pressure inside your lungs is lower. The higher pressure air outside flows in to lower pressure in chest cavity.
37
If you breathe in normally, then exhale normally into a spirometer, what lung volume are your measuring?
tidal volume
38
If you breathe in as deeply as you can, then exhale as much as you can into a spirometer, what lung volume are your measuring?
vital capacity
39
What is the main function of hemoglobin?
The main function of hemoglobin is to carry oxygen.
40
Flow of blood in pulmonary circuit & systemic circuit
Blood circulation to the lungs (short loop called pulmonary circuit) can be separated from blood circulation to the rest of the body (systemic circuit) with more heart chambers
41
Components of blood
Plasma (55%) - Has protein-rich liquid which is 90+% water. Also has serum, the fluid part of plasma. Red blood cells (45%) - Called erythrocytes. They carry oxygen & carbon dioxide, are biconcave, have no nucleus so that there is more space for hemoglobin, and the lifespan is 120 days. White blood cells & platelets (<1%) - Called leukocytes. Part of the immune system. It defends body against harmful substances/organisms.
42
Septum
Wall of tissue dividing left & right ventricles
43
Pericardium
Fluid-filled sac that surrounds and protects the heart
44
Coronary blood vessel
A blood vessel that circulates blood to and from the muscle cells of the heart
45
Chambers
The right atrium receives oxygen-poor blood from the body and pumps it to the right ventricle. The right ventricle pumps the oxygen-poor blood to the lungs. The left atrium receives oxygen-rich blood from the lungs and pumps it to the left ventricle. The left ventricle pumps the oxygen-rich blood to the body.
46
Coronary arteries/blood vessels Also, what causes heart sounds???
Supply blood to heart tissue Heart sounds are caused by the closing of heart valves
47
Semilunar valves
Prevents backflow of blood when ventricles relax Ex. Mitral & Aortic valves
48
Atrioventricular valves + chordae tendineae
Prevents blood flow of blood from ventricles to atriums. Supported by chordae tendineae - tendons that support the atrioventricular valves Ex. Pulmonary & tricuspid valves
49
Diastole & systole
The cardiac cycle is a complete heartbeat where atria (atriums) & ventricles contract and relax. There are 2 phases... Diastole - when ventricles are relaxed and filled up by blood Systole - when ventricles contract and emptied of blood
50
What are the 2 main components of blood? What percentage of each?
55% plasma 45% blood cells (mostly red blood cells)
51
Describe 2 characteristics of erythrocytes (red blood cells).
Any 2 of: RBC's have no nucleus; they contain hemoglobin, which carries oxygen; they are red when they carry oxygenated blood and blue when they carry deoxygenated blood; they make up almost all of the cells in blood; they are biconcave; they survive about 120 days....
52
Name 1 type of protein contained in blood. Also what cell is involved in blood clotting?
Any 1 of: albumins, globulins, fibrinogens Platelets
53
Name the 2 major blood vessels that bring blood to the heart.
the vena cava (superior & inferior), and the pulmonary veins
54
Name the 2 major blood vessels that take blood away from the heart.
the aorta & the pulmonary arteries
55
What is systolic blood pressure?
blood pressure while the ventricles in the heart are contracting
56
What causes the "lubb-dubb" sounds of the heartbeat?
the closing of the heart valves