29 Flashcards
(56 cards)
4 steps of food processing
Ingestion, digestion, absorption, egestion
Mouth function
Does physical digestion (bigger to smaller pieces) & chemical digestion (chemical bonds broken. Ex. Saliva’s enzymes)
Saliva has enzyme called amylase which digests starch. It also has mucus, which lubricates & helps with swallowing.
Esophagus
Epiglottis is a small flap of tissue that closes over trachea when swallowing. Bolus (the shape) of food moves down from esophagus to stomach due to peristalsis (wave-like contractions).
Stomach - Sphincters
Sphincters are circular muscles that control movement of food in & out of stomach.
Gastroesophageal sphincter controls entry of food, while pyloric sphincter controls the exit of food.
Stomach - Layers
Mucosa - innermost layer made of epithelial cells that secretes gastric juice (which has enzymes, acid, & mucus)
Muscle layer - breaks down food by contracting frequently, forming chyme (semi-liquid mixture of food & gastric juice). This soupy liquid enters the small intestine.
Stomach - Gastrin (mucus, HCI, pepsin)
Gastrin (hormone) helps release gastric juice from mucosa cells. Mucus coats & protects stomach lining. Hydrochloric acid (pH 2-3) kills bacteria & activates enzyme pepsin (from inactive pepsinogen), which digests proteins.
Small intestines - Size and what parts? Also what is its purpose?
2.5cm in diameter, up to 7m in length.
Parts
Duodenum - first 25-30cm; for digestion
Jejunum - digestion & some absorption
Ileum - absorption
The small intestine breaks down food and absorbs nutrients.
Small intestine - Inner surface (Villi, microvilli, lacteals)
Inner layers are folded into ridges. They have smaller folds/finger-like projections called villi. The villi have even smaller, microscopic projections called microvilli.
Nutrients go from mucosa in small intestine into capillary networks in villi.
These villi have network of capillaries that pick up absorbed nutrients (except digested fats). The fats are transported (absorbed) through small vessels called lacteals.
Chemical Digestion in Small Intestine (Duodenum) (Chyme > Prosecretin, Secretin, CCK)
Acidic chyme enters duodenum (through pyloric sphincter), and epithelial cells convert prosecretin to secretin. Fat in chyme causes the release of hormone CCK (cholecystokinin).
Role of Pancreas in Small Intestine - The hormones & enzymes they release (HCO3- ions, trypsinogen, trypsin, enterokinase, lipases)
Secretin (hormone) stimulates pancreas to release HCO3- (bicarbonate ions). These ions have a pH of 9, which inactivates the pepsin in chyme. The ions travel from pancreas to pancreatic duct and then into duodenum.
The hormone CCK (from duodenum) releases pancreatic juice (containing digestive enzymes & HCO3- ions) that signals the stomach to slow down digestion.
Pancreas also releases trypsinogen, which activates into trypsin (enzyme, after travelling from pancreas into duodenum, helps digest protein) by enzyme enterokinase.
It also releases lipases (enzyme), which help break down lipids (fats). Digested fats are absorbed through lacteals.
Role of Liver and Gall Bladder in Small Intestine
The liver creates bile which is stored in the gall bladder. Bile is a substance that emulsifies (breaks) fat down into smaller pieces (physical digestion).
Absorption in Small Intestine
In jejunum & ileum, through…
Passive transport - movement of materials across a cell membrane without use of energy. Uses osmosis (movement of water from area with more water to area with less water) and facilitated diffusion (diffusion of molecules across membrane through transport proteins). Moves materials down concentration gradient.
Active transport - movement of materials across a cell membrane with use of energy. Moves materials up concentration gradient.
Large intestine - Size and what parts? Also what is its purpose?
7.6cm in diameter, 1.5m in length. Cecum (with appendix) is the start of the large intestine, and is a pouch that receives material from small intestine.
Colon has 4 segments, and is the longest part.
There is also the rectum (last 20cm of large intestine) and the anus (the external opening).
The large intestine absorbs water & produces essential vitamins.
Egestion - What happens? Also, what is the role of dietary fiber in human egestion?
Rectum holds waste until eliminated as feces through anus.
Dietary fiber helps prevent/relieve constipation.
What are the 4 components of the digestive process?
ingestion, digestion, absorption, egestion
What enzyme is present in saliva? What nutrient does it digest?
amylase; It starts the digestion of starch (a carbohydrate).
What is the food called as it leaves the mouth? as it leaves the stomach?
bolus; chyme
In the human gastrointestinal tract, physical (mechanical) digestion of nutrients occurs in 2 different locations. Describe what happens in each of these locations.
-mouth: teeth chew food
-stomach: muscles contract frequently to break apart food
(Could also add small intestine, but it only applies to lipids: bile emulsifies fat)
What causes the food to move down the esophagus?
peristalsis (rhythmic contractions of muscles)
What 2 structures increase the internal surface area of the small intestine by 500 times?
(folds &) villi, microvilli
Name all of the organs that food passes through (in order) in the human digestive system, starting with the mouth.
mouth, esophagus, stomach, small intestine, large intestine, anus
Name 3 accessory organs to the digestive system.
any 3 of: liver, pancreas, gall bladder, salivary glands
Name the 2 muscles that allow food into and out of the stomach.
gastroesophageal sphincter & pyloric sphincter
What are the 3 components of the gastric juice in the stomach and what do they do?
mucus: protects the lining of the stomach from acid & enzymes
hydrochloric acid: kills pathogens, activates pepsinogen
pepsinogen: when activated (to pepsin), it digests proteins