VIH Flashcards

0
Q

vih 1 subtipos

A

tres grupos: m,n,o

m tiene 11 subtipos
b mas comun en usa, europa y aus
c en africa

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1
Q

clasificacion

A

vih 1 y 2

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2
Q

vh2 subtipos

A

6 en africa

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3
Q

estruc del vih

A

arn esferico, envoltura con glucopreinas, capside con dos arn positivo, nucleocapside icosaedrica. 2 arn de trasferencia

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4
Q

como esta compuesta la espicula

A

gp120 y gp41 y constituyen las glucoproteinas de la envoltura

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5
Q

como se le conoce a la region mas inmunogenicade la gp120

A

V3 y varia antigenicamente

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6
Q

que hace la trancriptasa inversa

A

elabora copias del DNA al RNA

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7
Q

es la plantilla para el rna viral

A

provirus

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8
Q

como comienza la rplicacion del vih

A

se une el gp120 y 41 a la superficie del CD4

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9
Q

cuales son los receptores quimiocinas

A

ccr5 y cxcr4

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10
Q

el principal determinante de la patogenia y la enfermedad provocado por el VIH es el

A

tropismo de linfo t y macrofagos

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11
Q

poblacion con mas riesgo

A

homo, drogadictod, receprotes de trasplantes, medico, hetero

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12
Q

vias de transmision

A

inoculacion de sangre, contacto sexual, sececiones vaginales, perinatal

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13
Q

donde se produce la infeccion

A

cel linfoides de submucosa vaginal y rectal y despues a ganglios

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14
Q

sintomas iniciales

A

gripe, mononucleosis, meningitis, aseptica, exantema

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15
Q

fase aguda de la infeccion

A

fiebre, adenopatias, cefalea, odinofagia, anorexia, vomito

16
Q

infecciones oportunistas

A

mycobacterium, candida, pneumocystitistoxoplasma, herpes simple

17
Q

tx

A
nucleosidos inhibidores transcriptasa: Acidotimidina
inhibidores no nucleosidos: neviparina
inhibidores de proteasa: ...avir
inhibidor integrasa: ralegravir
inhibidor de la union y fusion: ccr5
18
Q

dx

A

ELISA
Aglutinacion de latex
inmunofluorecencia