2A drug list

Question 1

What class of drug is alendronate?

Answer 1

Bisphosphonate

Question 2

Describe the MOA of alendronate

Answer 2

Inhibits RANK-L signaling to osteoclast by osteoblasts so decreases bone resorption

Question 3

What is alendronate used for?

Answer 3

Osteoporosis
Bone malignancy and myeloma
Long term steroids

Question 4

What class of drugs does atenolol belong to

Answer 4

Cardioselective beta-blocker(Only inhibits beta 1 on heart)

Question 5

What is atenolol used for?

Answer 5

Angina
Acute coronary syndrome
Arrhythmias: atrial fibrillation and atrial flutter

Question 6

When is atenolol contraindicated?

Answer 6

In absolute asthma

Question 7

Describe the MOA of atracurium

Answer 7

Muscle relaxant: competitively binds to cholinergic nicotinic/muscarinic receptors and neuromuscular junction and inhibit ACh action

Question 8

What type of drug is atracurium?

Answer 8

ACh M3 antagonist

Question 9

When is atracurium used?

Answer 9

Surgery

Question 10

What class of drug does bendroflumethiazide belong to?

Answer 10

Thiazide diuretics

Question 11

Describe the MOA of Bendroflumethiazide

Answer 11

Inhibits Na+ Cl- cotransporter in DCT

Question 12

What class of drug does cefuroxime belong to?

Answer 12

3rd generation cephalosporin (beta-lactam)

Question 13

What is cefuroxime used for?

Answer 13

Prostatitis, pyelonephritis, hospital-acquired pneumonia

Question 14

What class of drugs does celecoxib belong to?

Answer 14

Selective Cox-2 inhibiting NSAID

Question 15

What is celecoxib used for?

Answer 15

Pain relief in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis

Question 16

What is the main side effect of celecoxib?

Answer 16

Dizziness

Question 17

What kind of drug is chloramphenicol

Answer 17

Potent antibiotic

Question 18

What is chloramphenicol used for?

Answer 18

Eye drops for eye infections

Question 19

What type of drug is ciclosporin?

Answer 19

Calcineurin inhibitor

Question 20

Describe the MOA of ciclosporin?

Answer 20

Calcineurin activates T-cell response, ciclosporin inhibits this and causes immunosuppression

Question 21

What is ciclosporin used for?

Answer 21

Rheumatoid arthritis
Nephrotic syndrome
Crohn’s
Dermatitis
Sicca/Sjogren’s (eye drops)

Question 22

What drug class does ciprofloxacin belong to?

Answer 22

Fluoroquinolone

Question 23

What is ciprofloxacin used to treat?

Answer 23

Many infections, gram-negative bacteria
E.Coli
Salmonella
Shigella
Neisseria
Pseudomonas
Campylobacter
Chlamydia

Question 24

Describe the MOA of ciprofloxacin

Answer 24

DNA gyrate and topoisomerase inhibition

Question 25

Which drugs make up co-amoxiclav?

Answer 25

Amoxicillin Clavulanic acid

Question 26

What class of drug does co-amoxiclav belong to?

Answer 26

Beta lactam (A) and beta lactamase inhibitor (C)

Question 27

When is co-amoxiclav most useful?

Answer 27

Beta lactamase-producing bacterial strains where amoxicillin alone isn't sufficient

Question 28

What is co-amoxiclav used to treat?

Answer 28

Sinusitis UTI Skin/joint/dental infection

Question 29

What kind of drug is diamorphine?

Answer 29

Opioid analgesic, 2 times stronger than morphine (Heroin)

Question 30

What is diamorphine used for?

Answer 30

Short term analgesia Long term-tolerance, dependence, withdrawal

Question 31

What class of drug does dalteparin belong to?

Answer 31

Low molecular weight heparin

Question 32

Describe the MOA of dalteparin

Answer 32

Inhibits antithrombin 3 (anticoagulant)

Question 33

What is dalteparin used for?

Answer 33

DVT and PE to prevent risk of MI/stroke

Question 34

How is dobutamine administered?

Answer 34

IV only

Question 35

What class of drug is dobutamine?

Answer 35

beta 1 adrenergic antagonist

Question 36

What is dobutamine used to treat?

Answer 36

Cardiogenic shock and severe heart failure

Question 37

What class of drug does doxazosin belong to?

Answer 37

alpha-adrenergic antagonist (alpha-blocker)

Question 38

What is doxazosin used for

Answer 38

Hypertension Phaeochromocytoma and hypertensive crisis Benign prostatic hyperplasia (relaxes detrusor neck and makes it easy to pee)

Question 39

What is ephedrine used for?

Answer 39

Nose drops for nasal congestion Prevents low BP during anaesthesia

Question 40

What kind of drug is ephedrine and where is it found?

Answer 40

Stimulant Found directly in plants