2g Health Protection and communicable diseases Flashcards
(112 cards)
What is Incubation?
The time interval between initial contact with an infectious agent and the appearance of the first sign or symptom of the disease in question.
What is Communicability?
: Period of communicability is the time during which an infectious agent may be transferred directly or indirectly from an infected person to another person, from an infected animal to humans, or from an infected person to animals. Also known as the ‘infectious period’.
What is the Latent Period?
The period between exposure and the onset of the period of communicability. This may be shorter or longer than the incubation period.
What is Susceptibility?
The state of being susceptible (easily affected/infected). A susceptible person does not possess sufficient resistance against a particular pathogen to prevent contracting that infection or disease when exposed to the pathogen.
What is Immunity?
The condition of being immune, protected against an infectious disease conferred either by an immune response generated by immunisation or previous infection.
There are 4 types of immunity:
Active
Passive
Specific
Required
What are the different types of immunity?
Active
Passive
Specific
Required
What is active immunity?
Resistance developed by a host in response to a stimulus by an antigen (infecting agent or vaccine), usually characterised by antibody produced by the host.
What is passive immunity?
Immunity conferred by an antibody produced in another host and acquired naturally by an infant from its mother or artificially by administration of antibody-containing preparations e.g. anti-serum or immunoglobulin.
What is specific immunity?
A state of altered responsiveness to a specific substance acquired through immunisation or natural infection. In certain diseases this protection can last for the life of the individual.
What is aquired immunity?
Resistance acquired by a host as a result of previous exposure to a natural pathogen or foreign substance for the host e.g. immunity to measles following measles infection.
What is herd immunity?
The level of immunity in a population which prevents epidemics, based on the resistance to infection of a proportion of individual members of the group sufficient to prevent widespread infection amongst non-immune members.
The proportion required varies according to agent, transmission characteristics and distribution of immune and susceptibles within the population.
What is surveillance?
The continued watchfulness over the distribution and trends in the incidence of disease through the systematic collection, consolidation and evaluation of morbidity and mortality reports and other relevant data’
What is the purpose of surveillance?
Allows individual cases of infection to be notified and collated
Measures incidence of infectious disease, with changes potentially indicating an outbreak
Tracks trends in occurrence and risk factors of an infectious disease allowing targeted interventions
Enables priority setting and planning of control measures e.g. to a particular region
Evaluation of existing control measures
Syndromic surveillance may detect the emergence of new infections of public health importance.
What are the principles of good surveillance?
Start with a good case definition:
Must include clinical and/or microbiological criteria
Must be sensitive enough to detect cases, but also specific enough to prevent too many ‘false positives’. May include different levels of case definition e.g. ‘possible’, ‘probable’ and ‘confirmed’.
Collect data:
Multiple data streams may be used in combination to gain extra info (e.g. disease burden, high-risk groups)
Data collection should be systematic (systematic, regular and uniform)
Data analysis:
Data should be analysed to produce statistics: by time, place and person.
Care should be taken with timeliness, completeness, representation
Distribution of results:
Results should be distributed to those who require it, for instance via national bulletins (e.g. in national communicable disease epidemiology reports such as PHE’s Health Protection Report).
Implement actions and then continue surveillance to evaluate actions taken.
What are the different types of surveillance?
Active surveillance
Passive surveillance
Syndromic surveillance
Sentinel surveillance
Enhanced surveillance
What is
Active surveillance
Special effort to collect data and confirm diagnoses to ensure more complete reports, such as surveys and outbreak investigations
Encompasses formal and informal communications (such as phone calls or internet searches to seek information).
What is Passive surveillance?
Use of routine sources of information such as notifications, laboratory reports, and Hospital Episode Statistics (HES).
What is Syndromic surveillance?
The monitoring of symptoms, signs or syndromes instead of confirmed diagnosis.
Traditional public health surveillance relies on clinicians notifying public health authorities about diseases, which can lead to time delay from the reporting clinician or awaiting diagnostics.
By collation and analysis of real-time health data (such as presentations to primary care with a particular symptom e.g. influenza-like illness, rather than clinician notified diagnoses) which may indicate an important public health threat, ‘Syndromic surveillance’ allows for the earlier detection of outbreaks or health threats than would normally occur using traditional notification systems, and therefore earlier targeted action (CDC MMWR 2004).
What is Sentinel surveillance?
Rather than collecting data from all notifying clinicians, only a sample are asked to report data at a regional or national level, on a regular (e.g. weekly/monthly) basis.
What is Enhanced surveillance?
Enhanced surveillance is the collection of data above that collected for routine surveillance, generally at a patient level and often to design or evaluate an intervention or to aid control of more important health hazards.
For example, gaining epidemiological as well as microbiological information about MRSA bacteraemia cases in order to target and evaluate the effect of healthcare interventions on the incidence of the infection
What are some examples of sources of surveillance data?
Statutory notifications
Laboratory reports
Serological surveys
Sentinel reporting systems Routine Primary and Secondary Care utilisation data, e.g. in England, Hospital Episode Statistics (HES) data
Death certificates (limited use in industrialised countries because few infectious diseases lead to death)
Enhanced Surveillance for infections of public health importance to combine epidemiological and microbiological data, e.g. meningococcal disease, TB
Vaccine use (COVER statistics in England)
Sickness absence
Epidemic reports, e.g. respiratory illness outbreaks in care homes are monitored as part of influenza surveillance
Media reports
Social media activity
Animal reservoir and vector studies
What specific surveillance systems do we use for influenza?
Data collated by Respiratory Diseases Department (RDD) in the UKHSA.
Primary Care sentinel surveillance weekly returns service of consultation rates for influenza like illness (principle measure of flu activity).
Emergency Department attendances and NHS 111 (health advice helpline for the general public) cold and flu calls
Flusurvey.org.uk – online reporting of flu symptoms by the general public
Medical Officers of Schools Association (MOSA) scheme
Mortality data from Office for National Statistics (ONS) weekly death reports
Laboratory reports – Datamart surveillance scheme of positive influenza virology samples from selected laboratories; RCGP sentinel scheme – selected practices post nose and throat swabs from patients presenting with ILI for further characterisation by PCR
Hospital surveillance through the mandatory UK Severe Influenza Surveillance Scheme (USISS), monitoring critical care admissions of confirmed flu cases
Also, a USISS voluntary sentinel surveillance scheme for other hospitalised patients with confirmed influenza.
What specific surveillance systems do we use for influenza?
Data collated by Respiratory Diseases Department (RDD) in the UKHSA.
Primary Care sentinel surveillance weekly returns service of consultation rates for influenza like illness (principle measure of flu activity).
Emergency Department attendances and NHS 111 (health advice helpline for the general public) cold and flu calls
Flusurvey.org.uk – online reporting of flu symptoms by the general public
Medical Officers of Schools Association (MOSA) scheme
Mortality data from Office for National Statistics (ONS) weekly death reports
Laboratory reports – Datamart surveillance scheme of positive influenza virology samples from selected laboratories; RCGP sentinel scheme – selected practices post nose and throat swabs from patients presenting with ILI for further characterisation by PCR
Hospital surveillance through the mandatory UK Severe Influenza Surveillance Scheme (USISS), monitoring critical care admissions of confirmed flu cases
Also, a USISS voluntary sentinel surveillance scheme for other hospitalised patients with confirmed influenza.
What specific surveillance systems do we use for TB?
A statutory notification
Data collated and analysed by the UKHSA
Collects data on demographic, clinical and risk factor details, treatment outcome, drug sensitivity and species typing
Death certificates
TB incident and outbreak surveillance.