2nd Topic Flashcards
(33 cards)
Normal plt ct
150 to 450
In neonates is dt absent or dec megakaryocyte
Tar
Platelet consumption and rbc des
Congenital hemangiomata
Space occupying lession in bm
Myelophthisic process
Txt of congenital hemangiomata
Surgical removal
Allergic rxn or drug induced endothelial wall damage
Autoimmune vascular purpura
Chlorothiazide and diethylstilbesterol
Selective suppression of megakaryocyte
Drugs that cause endo damage
Quinine Procaine Penicillin Aspirin Sulfonamide Coumarin Sedatives
Small bv bleeding due to dec plt ct
Thrombocytopenia
Significant bleeding
Abnormal plt morphology
No plt glycoprotein
Bernard soulier syn
Spontaneous bleeding on skin
High plt destruction and ineffective plt prod
Giant plts
May hegglin anomaly
Dilutional loss
Chronic blood loss
High plasma level
Bm suppression resulting to dec all cell types
Aplastic anemia
Wiskoff aldrich syn assoc w
Immune def Hemorrhage Eczema Infxn Defect in prod and release of plt
Tar means
Thrombocytopenia with absent radius
Megakaryocyte disorder
Tar
Metastatic tumor, fibrosis, leukemia
Myelophthisic process
For enzyme plt protein synthesis
Iron
Deposition of amyloid
Amyloidosis
Marrow replacement. Inhibits thrombopoiesis.
Myelophthisic process
Exposure of plt to endothelial surfaces
Activate coag process
Consumption of endovascular injury
Non immune plt destruction
Dilution of plt ct
Excessive blood transfussion