3/16 Reading

Question 1

teratogen effects of isotretinoin?

Answer 1

facial and ear anomalies, heart defects

Question 2

what is MC cause of elevated AFP in pregnancy?

Answer 2

incorrect dating

Question 3

what is imaging for wilms tumor?

Answer 3

US

Question 4

what is elevated in neuroblastoma in kids?

Answer 4

VMA and metanephrines

Question 5

4 features of tetralogy of fallot

Answer 5

overriding aorta
VSD
right ventricular hypertrophy
pulm stenosis

Question 6

what imaging for tet of fallot? what is finding?

Answer 6

Xray…boot shaped heart

Question 7

what can keep PDA open? what can close it?

Answer 7

prostaglandin E keeps open….indomethacin closes

Question 8

what is truncus arteriosus?

Answer 8

one trunk comes from LV and RV

Question 9

what is total anomalous pulmonary venous return?

Answer 9

pulm veins to SVC instead of left atrium

Question 10

what happens in tricuspid atresis?

Answer 10

basically get failure of right side of heart and patient dependent on shunts

Question 11

what is splitting of S2 like in ASD?

Answer 11

fixed wide splitting

Question 12

murmur of ebstein anomaly?

Answer 12

holosystolic murmur like tricuspid regurgitation

Question 13

three main features of osteogenesis imperfecta?

Answer 13

fragile bones/fractures, blue sclera and deafnes

Question 14

what is issue in osteogenesis imperfecta?

Answer 14

collagen type 1

Question 15

which bone tumor responds to NSAIDs?

Answer 15

osteoid osteoma

Question 16

what is imaging finding of osteoid osteoma?

Answer 16

round central lucency with sclerotic margin

Question 17

fever and URI that leads to slapped cheek rash?

Answer 17

parvo 19/5th disease

Question 18

what is xray sign of epiglottisis?

Answer 18

thumbprint sign

Question 19

what is treatment of diptheria?

Answer 19

antitoxin…abx dont work

Question 20

two findings of B1 thiamine deficiency

Answer 20

wernicke and beriberi

Question 21

3 findings of B2 riboflavin deficiency

Answer 21

angular chelosis,stomatitis and glossitis

Question 22

findings of B3 or niacin deficiency

Answer 22

pellagra…dermatitis, diarrhea, dementia, dead

Question 23

what is deficient in tay sachs?

Answer 23

hexoaminidase a

Question 24

what are findings n tay sachs?

Answer 24

cherry red macula
ID
seizures

Question 25

what is deficient in niemann pick disease?

Answer 25

sphingomyelinase

Question 26

what are findings of niemann pick disease

Answer 26

cherry red macula hepatosplenomegaly neurodegeneration

Question 27

what is deficiency in gaucher disease?

Answer 27

b glucocerebrosidase

Question 28

findings of gaucher disease

Answer 28

hepatosplenomegaly lytic lesions gaucher cells

Question 29

fabry disease presents with what?

Answer 29

peripheral neuropathy

Question 30

what is deficient in fabry disease?

Answer 30

alpha galactosidase

Question 31

what is deficient in krabbe disease?

Answer 31

galactocerebrosidase

Question 32

features of krabbe disease

Answer 32

optic atrophy and developmental delay

Question 33

what are neurotransmitter changes in bipolar?

Answer 33

high NE and serotonin

Question 34

what is treatment of cyclothymic disorder?

Answer 34

mood stabilizers and psychotherapy

Question 35

what antipsychotic least associated with weight gain?

Answer 35

aripiprazole

Question 36

what antipsychotic has least risk for movement disorder?

Answer 36

quetiapine

Question 37

which antipsychotic has strongest associatin with prolonged QT?

Answer 37

ziprasidone

Question 38

three options for opiate withdrawal?

Answer 38

clonidine, methadone or buprenorphine

Question 39

what happens to pupils in opiate intoxication/

Answer 39

pinpoint

Question 40

rx of adjustment disorder?

Answer 40

psychotherapy