3 Acute Coronary Syndrome, part 1 Flashcards

1
Q

Remarks on bradycardia in ACS

A
  1. Bradycardic rhythms are more common with INFERIOR wall myocardial ischemia
  2. In the setting of an acute ANTERIOR wall infarction, bradycardia or new heart block is a poor prognostic sign
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2
Q

remarks on a new systolic murmur in ACS

A

The presence of a new systolic murmur is an ominous sign because it may signify
- papillary muscle dysfunciton
- flail leaflet of the MV with resultant MR
- VSD

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3
Q

Remarks on the ACS spectrum

A

STEMI is based on the ECG,
NSTEMI is based on cardiac biomarkers,
and unstable angina is based on history.

All in the setting of symptoms suggestive of ACS.

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4
Q

The single best test to identify patients with AMI upon ED presentation

A

12-lead ECG
Ideally obtain ECG within 10 minutes of presentation in those patients with symptoms suggestive of myocardial ischemia.

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5
Q

ECG findings of a true posterior MI

A

Initial R waves in V1 and V2 >0.04 s and R/S ratio ≥1;
Right-sided ECG shows 0.5-mm ST elevation in V7-V9

A posterior wall infarction does not produce Q-wave abnormalities in conventional leads and is diagnosed in the presence of tall R waves in V1 and V2

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6
Q

ECG findings of RV MI

A

ST elevation in II, III, and aVF
ST depression in lateral leads
ST elevation in RV leads V3R-V6R

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7
Q

ST-segment elevation in _____ is highly suggestive of right ventricular infarction

A

V4R

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8
Q

This finding predicts a right coronary artery occlusion in inferior wall AMIs

A

presence of STE in in lead III greater than that in lead II

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9
Q

ECG findings for anterior STEMI
from proximal LAD

A

STE in V1, V2, and V3 plus
STE of >2.5 mm in lead V1, or RBBB with Qwave, or both; or
ST-segment depression of >1 mm in leads II, III, aVF

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10
Q

ECG findings for anterior STEMI
from distal LAD

A

STE in V1, V2, and V3 plus
≤1 mm STdepression in leads II, III, aVF,
or STE in II, III, aVF

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11
Q

Findings that are suggestive of AMI in ECGs with LBBB

A

Concordant STE (strongly suggestive of AMI)
Concordant ST-segment depression (suggestive of AMI)
Excessive (>5 mm)) discordant STE (weakly suggestive of AMI)

[Sgarbossa criteria]

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12
Q

remarks on LBBB in ACS

A

Recognizing STEMI in the presence of LBBB is difficult, and due to this uncertainty and false catheterizaiton lab activation, new or susptected new LBBB alone has been removed from the most recent recommendations for emergency perfusion.

What matters in patients with LBBB is the presence of history suggestive of ACS.

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13
Q

ECG findings of Wellens’ syndrome

A

Deeply inverted or deep biphasic T waves
most prominent in V2 and V3,
often in V1 and V4,
and occasionally in V5 and V6

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14
Q

Significance of Wellens’ syndrome

A

Assoc’d with critical stenosis of LAD
Considered an ACS equivalent
Because of the high incidence of critical coronary stenosis and the potential for acute infarction, patients with Wellen’s syndrome should receive early interventional management

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15
Q

Chest pain in Wellen’s syndrome

A

T waves of Wellens’ syndrome are usually visible when the patient is pain free and may normalize when pain recurs
- repeating the ECG when pain resolves or recurs can aid in detection of tehse dynamic changes

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16
Q

Remarks on ST-segment elevation and management decisions

A

Patients with diagnostic ST-segment elevation on their initial ECG do not require serum marker measurement to make treatment and disposition decisions.

17
Q

remarks on high-sensitivity troponin

A

Authors of large observational studies suggest that a single undetectable high-sensitivity troponin plus no ECG evidence of ischemia identifies patients at a very low risk for ACS

A serial high-sensitivity troponin interval as short as 2 hours coupled with a low Thrombolysis in Myocardial Infarction risk score (<2) virtually excludes AMI

18
Q

Remarks on degree of troponin elevation

A
  1. Any measurable elevated troponin is always worse than no elevated troponin.
  2. More troponin elevation is always worse than less troponin elevation with respect to prognosis.
19
Q

Remarks on significance of troponin elevation

A

Troponin elevation is specific for myocardial injury,
but elevation does not indicate the mechanism of injury.

20
Q

Non-ischemic causes of troponin elevations include:

A

Pulmonary hypertension
Arrhythmias
Pulmonary embolism
Aortic dissection

Burns
Extreme exertion (e.g., endurance athletes)
Acute neurologic disease (e.g., stroke, SAH)
Respiratory failure
Sepsis