3 classes of Hormones

Question 1

Peptide/Protein
Synthesis
Release
Transport
Circulatory 1/2 life
Receptor type

Answer 1

Synthesis: Produced inactive forms & stored in vesicles
Release: Exocytosis
Transport: Dissolved in plasma
Circulatory 1/2 life: Minutes
Receptor type: Membrane bound receptors

Question 2

Steroid
Synthesis
Release
Transport
Circulatory 1/2 life
Receptor type

Answer 2

Synthesis: Made on demand from cholesterol
Release: Diffusion
Transport: Bound to carrier proteins
Circulatory 1/2 life: 100’s of mins
Receptor type: Cytoplasmic or nuclear receptors

Question 3

Amino-acid derived: Catecholamines
Synthesis
Release
Transport
Circulatory 1/2 life
Receptor type

Answer 3

Amino-acid derived: Catecholamines
Synthesis: Proced & stored in vesicles
Release: Exocytosis
Transport: Dissolved in plasma
Circulatory 1/2 life: Less than a min.
Receptor type: Membrane bound receptors

Question 4

Amino-acid derived : Thyroid
Synthesis
Release
Transport
Circulatory 1/2 life
Receptor type

Answer 4

Amino-acid derived: Thyroid
Synthesis: Produced & stored
Release: Protein transport
Transport: Bound to carrier proteins
Circulatory 1/2 life: Days
Receptor type: Nuclear receptors