3: Microbiology of UTI Flashcards Preview

Renal Week 4 2017/18 > 3: Microbiology of UTI > Flashcards

Flashcards in 3: Microbiology of UTI Deck (66)
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1

What is a UTI?

Microorganisms in the urinary tract which are causing INFECTIOUS SYMPTOMS

2

What is a lower UTI?

Confined to the bladder (cystitis)

3

What is an upper UTI?

Infection involving the ureters AND/OR kidneys

(pyelonephritis)

4

Urine is normally ___.

sterile

5

What is a complicated UTI?

Symptoms of UTI (e.g dysuria, urgency, increased frequency) with any of:

SYSTEMIC SYMPTOMS (fever, rigors, N&V...)

RENAL STONES

ANATOMICAL ABNORMALITIES

6

Does bacteruria mean infection?

Not without symptoms

7

What is a common site for colonisers of the urinary tract?

Catheter

8

(Men / women) are more likely to develop UTIs.

women

shorter, wider urethras

sex

pregnancy

9

People with ___ are more likely to get UTIs.

catheters

10

What are the two routes of infection in UTI?

Ascending route

Haematogenous

11

What is the most common organism causing UTIs?

E. coli

12

Why is E. coli well adapted to causing UTIs?

Common bowel commensal

Have fimbriae (sticky appendages which let them climb all over the place)

13

Which investigations are used to

a) rule out

b) properly diagnose

UTIs?

a) Dipstick

b) Urine culture

14

What is the best investigation for UTI?

Urine culture

15

What are coliforms?

Gram negative bacilli

most commonly E. coli

16

E. coli is also called a ___ fermenter.

lactose fermenter

along with Klebsiella, Enterobacter

17

What organisms commonly cause UTIs?

Escherichia

Klebsiella

Enterobacter

Proteus

Pseudomonas

18

What does E coli produce to cause sepsis?

Endotoxin

19

What renal disease is Proteus associated with?

Renal stones

particularly struvite stones

20

Which UTI organism is associated with renal stones?

Proteus

21

Which type of renal stone is commonly seen in Proteus infection?

Staghorn calculus

22

Is Pseudomonas a coliform?

NO

but it is a Gram -ve bacillus

23

What is Pseudomonas UTI associated with?

Catheters

Surgery

24

How is Pseudomonas UTI treated?

Ciprofloxacin

25

How does ciprofloxacin work?

Affects bacterial DNA

26

What are the 4Cs?

Co-amoxiclav

Ciprofloxacin

Clindamycin

Cephalosporins

27

What's the difference between Enterobacter and Enterococcus?

Enterobacter is a Gram -ve bacillus

Enterococcus are Gram +ve

28

What is a Gram positive coccus which causes UTI?

Enterococcus (faecalis)

Staph. saphrophyticus

29

What is a type of Staphylococcus associated with UTIs in women of child bearing age?

Staph. saphrophyticus

30

What are the symptoms of UTI?

Dysuria

Haematuria (not always)

Nocturia

Increased frequency

Constitutional symptoms