Endo

Question 1

Zona glomerulosa

Answer 1

Aldosterone

Question 2

Alpha islet cells of the pancreas

Answer 2

Glucagon

Question 3

Hyperpigmentation of palmar creases

Answer 3

Addisons

Question 4

Dexamethasone suppression test

Not suppressed at low but suppressed at high

Answer 4

Cushing’s disease

Question 5

Dexamethasone suppression test

Not suppressed at either and high ACTH

Answer 5

Ectopic ACTH syndrome (e.g. adrenal tumour)

Question 6

Dexamethasone suppression test

Not suppressed at either and low ACTH

Answer 6

Primary hypercortisolism

Question 7

Phaeochromocytoma signs/symptoms

Answer 7

Headache
Perspiration
Palpitations
Polyuria
Hypertension

Question 8

Ketones

Answer 8

T1DM

Question 9

Metformin

Answer 9

Reduces insulin resistance peripherally and decreases hepatic glucose production
Enhances weight loss

Question 10

Sulphonylurea

Answer 10

Increases insulin secretion

S/E: weight gain and hypoglycaemia

Question 11

Carbimazole

Answer 11

Treat hyperthyroidism

S/E: agranulocytosis

Question 12

Primary aldosteronism

Signs/symptoms

Answer 12

Elevated BP
Muscle cramps (hypocalacemia)
Muscle weakness (hypokalaemia)
Headaches

Question 13

Zona fasciculate

Answer 13

Cortisol

Question 14

Zona reticularis

Answer 14

Testosterone and oestrogen

Question 15

Painless lymphadenopathy, Reed-Sternberg cells, good prognosis

Answer 15

Hodgkins

Question 16

Leydig cells

Answer 16

Secrete testosterone and DHEA