B R E A S T

Question 1

What causes skin dimpling in breast cancer

Answer 1

Traction on cooper’s ligaments

Question 2

Venous drainage is largely responsible for mets to spine via which plexus?

Answer 2

Batson’s plexus

Question 3

Tx of a 35 y.o. female presenting with 1 month history of spontaneous unilateral bloody nipple discharge. Radial compression of involved breast results in expression of blood at 12 o clock position.

Answer 3

Intraductal papilloma –subareolar mass. Excise affected duct.

Question 4

Tx of Paget’s Disease of the nipple

Answer 4

Modified radical mastectomy

Question 5

Tx of Inflammatory CA of breast

Answer 5

Most lethal :(. Consists of CHEMO followed by surgery and/or radiation. Greater than 75% of pets have axillary mets at time of dx of inflammatory breast CA. Distant mets are common.

Question 6

In pregnant patient, tx of stage I or II cancer

Answer 6

Modified radical mastectomy

Question 7

If LN are positive in pregnant patient, when do you do chemo?

Answer 7

Delayed until 2nd trimester.

Question 8

First screening mammo at what age?

Answer 8

35.

Question 9

Annual mammo after what age?

Answer 9

50

Question 10

Recommended chemo for breast CA

Answer 10

CAF (cyclophosphamide, adriamycin, 5-FU) or CMF (methotrexate instead of adriamycin)

Question 11

Prognosis of breast CA depends most on what?

Answer 11

Stage, rather than histologic type.