UTI 2 Flashcards
what is the most valuable lab test for diagnosing a UTI
urinalysis/ pyuria
WBC casts in urine indicate what
pyelonephritis
all women with acute cystitis have what
pyuria (WBC cells in urine)
what is common in cystitis but not urethritis
hematuria
what detects pyuria
leukocyte esterase in urine dipsticks
what detects enterobateriaceae in UTI
nitrite in urine dipsticks
why are urine cultures now important in UTIs
to tell antibiotic resistance
how is acute cystitis treated
100 mg nitrofurantoin BID for 5 days
if CrCl is less than 50, how is acute cystitis treated
Bactrim DS for 3 days
or
fosfomycin 3g one time dose
what are 3 treatments for acute cystitis
100 mg nitrofurantoin BID for 5 days
Bactrim DS for 3 days
fosfomycin 3g one time dose
when should Bactrim not be used for acute cystitis
resistance more than 20% or used for UTI in past 3 months
what are 2 alternative drugs for acute cystitis treatment
- fluoroquinolones: cipro or levo
2. b-lactams
what are the outpatient therapy of uncomplicated pyelonephritis
PO fluoroquinolone:
cipro 500 for 7 days; or levo 750 for 5 days
Bactrim DS 14 days BID
PO B-lactams for 10-14 days
what are the inpatient therapy of uncomplicated pyelonephritis
- fluoroquinolone
- aminoglycoside w/ or w/out ampicillin
- cephalosporin
- carbapenam
the addition of one dose of ceftriazone or an aminoglycoside is recommended for treating acute uncomplicated pyelonephritis when?
- fluoroquinolone resistance over 10%
- Bactrim susceptibility is unknown
- PO B-lactam is used
