Exam I-In class Activities-xerostomia & ulcers

Question 1

What is the classification of SAL-MET-EROL?

Answer 1

A LONG acting Beta-2 Agonist

Question 2

How does SalMetErol lead to Xerstomia?

Answer 2

Stimulation of the Sympathetic Nervous system(beta-2 agonist) will cause less salivation and more mucus salivation

Question 3

What class of drug is Ipra-Tro-Pium? How does it cause dry mouth?

Answer 3

Anti-Muscarinic. Blocking parasympathetic activity blocks normal watery saliva production. Sympathetic NS runs unopposed.

Question 4

What class of drug is Oxy-But-y-NIN? How does it cause dry mouth?

Answer 4

Anti-Muscarinic-Pill form will block M3 receptors on salivary glands and the sym ns runs unopposed

Question 5

How does Benedryl cause dry mouth?

Answer 5

the anti-histamine CROSS reacts with muscarinic receptors (especially high dose) causing blockage of the parasym activity

Question 6

What class of drug is Hydro-Chloro-Thi-Azide? How does it cause dry mouth?

Answer 6

A diuretic, causes dry mouth through dehydration

Question 7

What class of drug is Phenyl-Eph-Rine? How does it cause dry mouth?

Answer 7

A Alpha-1 Adrenergic Agonist in sudafed. Binding to alpha-1’s causes vasoconstriciton to the salivary glands which means less saliva!

Question 8

What class of drug is Benz-Trop-Ine? How does it cause dry mouth?

Answer 8

An Anti-Muscarinic for the Brain (treats Parkinsons-LATE stage).

Question 9

What type of drug is Pilo-Carpine? How does it relieve dry mouth?

Answer 9

Its a ParasympathoMimetic (muscarinic agonist). Promotes parasym activity and therefore more saliva!

Question 10

What class of drug is Cev-I-Mel-ine? how does it relieve dry mouth?

Answer 10

A parasymphatoMimic to enhance saliva production

Question 11

How does Biotene help relieve dry mouth?

Answer 11

Wettens the mouth and balances pH

Question 12

What is the most likely reason why a Pt would have Candadisis while using Fluticasone & Albuterol?

Answer 12

Both are oral steroids and are suppressing the immune system when getting stuck in the mouth. Try a spacer, rinse after inhaling, or powder inhaler.

Question 13

What class of drug is Keto-pro-fen? How would it lead to an ulcer?

Answer 13

An NSAID (an intense Ibuprofen). NSAIDs are COX inhibitors that block not only inflammatory prostaglandin production, but also physiological prostaglandins (COX-1 and COX-2). Prostaglandin is a Mucus stimulant, block it you block Mucus production.

Question 14

How would you treat a Pt with an Ulcer while on Warfarin?

Answer 14

Use a different NSAID like Tylenol (not a COX inhibitor)

Question 15

What class of drug is Clar-ithro-mycin? How does it work?

Answer 15

Its a MacroLide(antibiotic) -it targets bacterial ribosomes and stops protein production

Question 16

What class of drug is Amoc-i-cillin? How does it work?

Answer 16

Its a Penecillin-stops bacterial cell wall production.

Question 17

What class of drug is Eso-Mep-Razole? How does it work?

Answer 17

A PPI (Proton Pump Inhibitor). Stopping acid production in the Parietal Cells of the stomach.

Question 18

What three drugs are used in Triple Therapy? For what condition?

Answer 18

Peptic Ulcer Disease..2 AntiBiotics (H. Pylori is TOUGH) and a PPI.

Question 19

What class of drug is Ran-it-id-ine? How does it fight ulcers?

Answer 19

It is a Histamine receptor blocker. Blocking histamine blocks one stimulant on Paritetal cells to produce H+

Question 20

Why would just taking Tums not really treat PUD?

Answer 20

It is merely neutralizing Acid already made. It is not addressing the H. Pylori and it is not slowing down acid production.