Immunophenotyping Flashcards

1
Q

Lymphoid antigens: T lineage

A

CD1a, CD2, CD3, CD4, CD5, CD7, CD8

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2
Q

Lymphoid antigens: B lineage

A

CD19, CD20, CD22

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3
Q

Myeloid antigens: generic

A

CD13, CD15, CD33, CD117, MPO

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4
Q

Myeloid antigens: sub-lineage association

A
Megakaryocytes = CD41, CD61
Monocytes = CD14
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5
Q

Markers of immaturity

A

CD34 (AML & ALL)
TdT (ALL)
CD117 (AML)
CD1a (restricted to immature T cells)

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6
Q

CD34+, CD10+, CD19+, CD20-

A

B-ALL

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7
Q

CD3+, CD1a+, CD4-8 dual+ (NO CD10)

A

T-ALL

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8
Q

CD1a

A

immature T cells

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9
Q

CD10+, CD19+, CD20+

A

Burkitt Lymphoma

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10
Q

CD19+

CD20+

A

Diffuse large B-cell lymphoma

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11
Q

CD5-
CD10-
CD19+
CD20+

A

Extranodal marginal zone lymphoma (MALToma)

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12
Q

CD5-
CD10+
CD19+
CD20+

A

Follicular Lymphoma

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13
Q
CD5+ 
CD10-
CD19+
CD20+
CD23-
A

Mantle Cell Lymphoma

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14
Q

CD15+
CD30+
CD20-
CD45-

A

Classical HL

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15
Q

CD15-
CD30-
CD20+
CD45+

A

Nodular lymphocyte predominate Hodgkin Lymphoma (NLPHL)

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16
Q
CD19+
CD20+
CD11c+
CD22 bright
TRAP+
A

Hairy Cell Leukemia

17
Q

CD4+

CD25+

A

Adult T-cell Leukemia/Lymphoma