3.1 Flashcards

1
Q

increased rate of
destruction/lysis of RBCs, shortening their life span

A

HEMOLYSIS/ HEMOLYTIC DISORDER

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2
Q

What condition reduced tissue oxygenation

A

HEMOLYSIS/ HEMOLYTIC DISORDER

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3
Q

what condition increased erythropoietin production

A

HEMOLYSIS/ HEMOLYTIC DISORDER

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4
Q

What anemia when the rate of RBC destruction EXCEEDS the
increased rate of RBC production

A

HEMOLYTIC ANEMIA

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5
Q

What classification of hemolytic anemia is Rapid onset/ sudden, episodic, paroxysmal.

A

Acute

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6
Q

what classification hemolytic anemia is Hemolysis either disappears or subsides between periods

A

acute

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7
Q

what classification of hemolytic anemia Patient’s condition may return to normal

A

Acute

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8
Q

What classification of hemolytic anemia is Paroxysmal Cold Hemoglobinuria

A

acute

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9
Q

What classification of hemolytic anemia is Hemolytic transfusion reaction

A

acute

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10
Q

RBC life span is chronically shortened. Gradual decrease in RBCs.

A

chronic

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11
Q

Bone marrow compensates. Anemia is evident when BM cannot
generate cells fast enough.

A

chronic

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12
Q

what classification of hemolytic anemia is G6PD?

A

chronic and Intrinsic and inherited

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13
Q

what classification of hemolytic anemia is Chemicals/Drugs/infectious agents

A

chronic and acquired

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14
Q

what classification of hemolytic anemia is Thalassemia major

A

chronic

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15
Q

What hemolytic anemia is due to a defect within the rbc and usually inherited

A

intrinsic

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16
Q

classification of hemolytic anemia of Hereditary spherocytosis

A

intrinsic and inherited

17
Q

classification of hemolytic anemia of PK deficiency

18
Q

classification of hemolytic anemia of sickle cell disease

A

intrinsic and inherited

19
Q

Hemolysis is caused by a source outside the RBC and Usually acquired.

20
Q

Hemolytic anemia that causes may be immunohemolytic, traumatic, microangiopathic, or
infectious/chemical agents

21
Q

Paroxysmal nocturnal hemoglobinuria is an acquired disorder with intrinsic defect. What hemolytic classification is this?

22
Q

Prosthetic heart valve

A

extrinsic and acquired and INtravascular fragmentation

23
Q

malarial infection

A

extrinsic and acquired

24
Q

May be a result of abnormalities in enzymes, hemoglobin
synthesis, membrane defects or defective genes passed on by
parents to offspring.

25
Thalassemia
INHERITED
26
Individuals who previously had a normal red blood cell system WHAT HEMOLYTIC ANEMIA?
ACQUIRED
27
Some types of ________ hemolytic anemia may be temporary or life long ( chronic).
acquired
28
Lysis is inside the blood vessel/ within the blood stream
INTRAVASCULAR ~ FRAGMENTATION
29
Fragmentation- trauma to the RBC membrane which causes lysis
INTRAVASCULAR ~ FRAGMENTATION
30
Microangiopathic hemolysis
acquired, intravascular-fragmentation
31
Fragmentation- trauma to the RBC membrane which causes lysis
INTRAVASCULAR ~ FRAGMENTATION
32
Hemolysis outside the vasculature: within the Reticuloendothelial system/ Mononuclear phagocyte system (Spleen, Liver, Lymphnodes)
EXTRAVASCULAR ~ MACROPHAGE MEDIATED
33
Most pathologic hemolysis is extravascular and occurs when damaged or abnormal rbcs are removed from circulation.
EXTRAVASCULAR ~ MACROPHAGE MEDIATED
34
Hereditary Membrane defects
EXTRAVASCULAR ~ MACROPHAGE MEDIATED
35
Splenomegaly
EXTRAVASCULAR ~ MACROPHAGE MEDIATED