3.1 quiz Flashcards

1
Q

bone scan

A

examines skeletal abnormalities through use of radio tracers

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2
Q

MRI

A

produces images of internal soft tissues through use of radio waves and magnets

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3
Q

CT scan

A

produces cross sectional images of soft tissues

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4
Q

x-ray

A

uses ionization radiation to produce two dimensional images of dense tissues

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5
Q

risk factor

A

something which increases risk of susceptibility

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6
Q

multinuclearity

A

having more than one nucleus

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7
Q

nuclear blebbing

A

odd shaped nuclei in cancer cells

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8
Q

contact inhibition

A

enables noncancerous cells to cease proliferation and growth when they contact each other

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9
Q

replicative senescence

A

when a normal somatic cell reach irreversible stage of cell cycle arrest following multiple rounds of replication

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10
Q

biopsy

A

the removal and examination of tissue, cells, or fluids from the body

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11
Q

cancer

A

a malignant tumor of potentially unlimited growth that expands locally and systemically

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12
Q

tumor suppressor gene

A

keeps cell division in check

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13
Q

proto-oncogene

A

a gene with potential to cause cancer but requires some alteration to become an oncogene

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14
Q

oncogene

A

a gene with potential to make a normal cell cancerous

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15
Q

osteosarcoma

A

bone cancer

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16
Q

metastasis

A

development of secondary malignant growths at a distance from primary site of cancer

17
Q

apoptosis

A

changes that happen in a cell as it undergoes programmed death, a trigger causes suicide proteins in the cell that needs to die

18
Q

dna replication

A

genes in a cell are replicated

19
Q

cell cancer characteristics

A
  • large number of irregularly shaped cells clumped together
    -lose specialized cell features
    -cells vary in size and shape
    -large, variably shaped nucleus
    -disorganized arrangement of cells
20
Q

yellow microarray

A

equal gene expression

21
Q

black microarray

A

no expression in gene

22
Q

green microarray

A

decreased expression in cancerous cells

23
Q

red microarray

A

increased expression in cancerous cells

24
Q

where does dna for a microarray come from?

A

it comes from a tissue sample from the patient

25
how does dna for a microarray become double stranded?
primers start and a pcr reaction creates the other strand of DNA
26
positive correlation coefficient
gene expression profiles behave similarily
27
negative correlation coefficient
gene expression profiles behave in opposite ways
28
one correlation coefficient
gene expression profiles behave identically
29
zero correlation coefficient
gene expression profiles behave in an unrelated manor
30
what can correlation coefficient tell us
asses the strength of associations between data variables
31
carcinoma
epithelial tissue
32
sarcoma
connective and muscle tissue
33
leukemia
blood
34
lympthoma
lymphatic system
35
how can oncogenes cause cancer
because they are a mutated gene and can start to grow out of control and prevent apoptosis
36
how can tumor suppressor gene cause cancer
the lack of a tumor suppressor gene is unable to stop cells from replicating and won't be able to stop them