Respiratory Viruses

Question 1

What do they believe is the most common cause of croup?

Answer 1

parainfluenza virus

Question 2

Is RSV common?

Answer 2

yes most kids are likely to be infected by age 2

Question 3

What are the three most common causes of a cold?

Answer 3

1. rhinovirus
2. coronavirus
3. influenza virus

Question 4

Which virus is specifically adapted to the coolness of the upper airway?

Answer 4

rhinoviruses

Question 5

Which virus have an infection pattern of: acute infection with replication confined to mucosal surface?

Answer 5

1. picornavirus - rhinovirus
2. coronavirus
3. paramyxovirus - parainfluenza and RSV
4. orthomyxovirus - influenza

Question 6

What are three viruses that are known for their persistant replication?

Answer 6

EBV, adenovrius, papillomavirus

Question 7

Which viruses are known to spread systemically?

Answer 7

1. paramyxovirus - mumps, measles
2. herpesviruses - EBV, VZV, HHV6, CMV
3. Rubella
4. picornavirus

Question 8

What type of virus is a coronavirus?

Answer 8

(-) ssRNA

Question 9

Most strains of coronavirus cause a cold, what do the rare new strains cause?

Answer 9

lethal respiratory diseases

SARS and MERS

Question 10

What does “myxo” mean

Answer 10

mucus

Question 11

What type of virus is influenza?

Answer 11

segmented (-) ssRNA

enveloped

Question 12

Where does the influenza virus replicate?

Answer 12

in the nucleus

Question 13

What type of virus is a paramyxovirus?

Answer 13

nonsegmented (-) ssRNA

Enveloped

Question 14

where does the paramyxovirus replicate?

Answer 14

in the cytoplasm

Question 15

What are the symptoms in the flu caused by?

Answer 15

dying epithelial cells, interferon, T cells

Question 16

Do antibodies kill the virus?

Answer 16

no but they provide future protection

Question 17

What are the antivirals for influenza called?

Answer 17

tamiflu and relenza

Question 18

How many and what type of strains does the flu vaccine protect against?

Answer 18

3

1. H1N1 -A
2. H3N2 - A
3. Yamagata - B

Question 19

parainfluenza virus and RSV cause what disease?

Answer 19

croup

Question 20

When do infections with parainfluenza virus peak?

Answer 20

in the winter months

Question 21

What type of virus is the adenovirus?

Answer 21

icosahedral, naked, DNA

Question 22

What are the three common sites of infection for the adenovirus?

Answer 22

GI tract, Respiratory tract, mucoepithelial

Question 23

How is adenovirus spread?

Answer 23

aerosol, close contact, fecal oral, optho instruments

Question 24

When does the adenovirus peak?

Answer 24

NOT seasonal - constant presence

Question 25

Where are three environments that the adenovirus is notorious for infectiong?

Answer 25

day cares, military camps, swimming clubs