Neoplasia IX Flashcards

1
Q

In which neoplastic conditions are psammoma bodies found?

A

Papillary adenocarcinoma of the thyroid, serous papillary cystadenocarcincoma of the ovary, meningioma, malignant mesothelioma (pneumonic PSaMMoma- Papillary (thyroid), Serous (ovary), Meningioma, Mesothelioma) (p.223)

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2
Q

What are the top three cancers in terms of incidence in the US in men?

A

Prostate (32%), Lung (16%), Colon/rectum (12%) (p.224)

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3
Q

What are the top three cancers in terms of incidence in the US in women?

A

Breast (32%), Lung (13%), Colon/rectum (13%) (p.224)

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4
Q

What are the top two cancers in terms of mortality in the US in men?

A

Lung (33%), Prostate (13%) (p.224)

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5
Q

What are the top two cancers in terms of mortality in the US in women?

A

Lung (23%), Breast (18%) (p.224)

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6
Q

How has lung cancer incidence in the US changed over time in men compared to women?

A

Lung cancer incidence has dropped in men but has not changed significantly in women (p.224)

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7
Q

What is the overall leading cause of death in the US? Second leading cause of death?

A

Heart disease is the overall leading cause of death in the US; cancer is the second leading cause (p.224)

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8
Q

Rank the cancers in decreasing order according to liklihood of metastasis to the brain.

A

Lung> breast > genitourinary > osteosarcoma > melanoma > GI (p.224)

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9
Q

What kinds of primary tumors most commonly metastasize to the brain?

A

Lung, breast, genitourinary, osteosarcoma, melanoma, GI (p.224)

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10
Q

What kinds of primary tumors most commonly metastasize to the liver?

A

Colon, stomach, pancreas (p.224)

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11
Q

What kinds of primary tumors most commonly metastasize to the bone?

A

Prostate, breast, lung, thyroid, testes (p.224)

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12
Q

Rank the cancers in decreasing order according to liklihood of metastasis to the liver.

A

Colon&raquo_space; stomach > pancreas (p.224)

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13
Q

Rank the cancers in decreasing order according to liklihood of metastasis to the bone.

A

Prostate, breast > lung > thyroid, testes (p.224)

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14
Q

About what percentage of brain tumors are due to metastases?

A

50% (p.224)

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15
Q

Describe the characteristics of tumors that have metastasized to the brain.

A

Typically multiple, well-circumscribed tumors at the gray/white matter junction (p.224)

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16
Q

What are the two most common sites of cancer metastasis after the regional lymph nodes?

A

Liver and lung (p.224)

17
Q

Are bone metastases or primary bone tumors more common?

A

Metastases are much more common (p.224)

18
Q

Where are bone metastases most frequently localized?

A

The axial skeleton (p.224)

19
Q

What type of bone lesions are characteristic of metastatic lung cancer?

A

Lytic lesions (p.224)

20
Q

What type of bone lesions are characteristic of metastatic prostate cancer?

A

Blastic lesions (p.224)

21
Q

What type of bone lesions are characteristic of metastatic breast cancer?

A

Lytic and blastic lesions (p.224)