Tumor Immunotherapy

Question 1

Which two types of immunotherapy is there

Answer 1

Passive - don’t rely on host IS. In vitro production of Ab that is injected into patient

Active - Rely on host IS. Either foreign antigen is introduced and the host needs to create an immune response (as vaccine) or host own cells are collected and ex vivo stimulated to respond towards a certain antigen and reinfused into patient

Question 2

What is adoptive cellular immunotherapy

Answer 2

Adoptive Cellular immunotherapy is a form of active immunotherapy where cells are ex.vivo stimulated towards an antigen or just increased in nr and reinfused into patient.

The patients cell can also be genetically engineered ex.vivo to make the patients T cells to recognize a certain antigen and then reinfused