Lymphocytes

Question 1

What are the components of innate immunity?

Answer 1

1. Neutrophils
2. Macrophages
3. Monocytes
4. Dendritic Cells
5. Natural Killer cells
6. complement

Question 2

What is unique about natural killer cells?

Answer 2

They don’t need and MHC I complex (mostly viral)

Question 3

What is the mechanism for innate immunity?

Answer 3

Germline encoded

Question 4

Describe innate immunity resistance

Answer 4

• persists through generations

- unchanged within an organism’s lifetime

Question 5

How fast does the innate immune response to pathogens occur?

Answer 5

rapid- minutes to hours

Question 6

What are the physical barriers in innate immunity?

Answer 6

Epithelial tight junctions and mucus

Question 7

What are the secreted proteins in an innate immune response?

Answer 7

1. Lysozyme
2. Complement
3. C-reactive protein
   4 . Defensins

Question 8

What are defensins?

Answer 8

They bind and create pores

Question 9

How are pathogens recognized in an innate immune response?

Answer 9

Toll-like receptors recognize pathogen associated molecular patterns (PAMPs).

Question 10

PAMP

Answer 10

pattern associated molecular pattern recognized by TLRs

Question 11

Examples of PAMPs

Answer 11

• LPS
• flagellin
• ssRNA