Sympathomimetics Flashcards

1
Q

Which receptors do albuterol and salmeterol target?

A

B2 > B1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the applications for albuterol and salmeterol?

A

Albuterol for acute asthma, salmeterol for long-term asthma or COPD control.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which receptors does dobutamine target?

A

B1 > B2 > alpha

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the applications for dobutamine?

A

heart failure (inotropic > chronotropic), cardiac stress testing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which receptors does dopamine target?

A

D1 = D2 > B > alpha

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the applications for dopamine?

A

Unstable bradycardia, HF, shock

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which effects of dopamine predominate at high doses?

A

Inotropic and chronotropic alpha effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which receptors does epinephrine target?

A

B > alpha

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the applications for epinephrine?

A

Anaphylaxis, asthma, open-angle glaucoma. Alpha effects predominate at high doses.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which has stronger B2 action, epi vs. noepi?

A

Epi is significantly stronger.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which receptors does isoproterenol target?

A

B1 = B2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the applications for isoproterenol?

A

Electrophysiologic evaluation of tacharrythmias. Can worsen ischemia.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which receptors does norepinephrine target?

A

a1 > a2 > B1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the applications for norepinephrine?

A

Hypotension (septic shock). *Decr renal perfusion.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which receptors does phenylephrine target?

A

a1 > a2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the applications for phenylephrine?

A

Hypotension, ocular procedures, rhinitis

17
Q

How does amphetamine work?

A

Indirect general agonist, reuptake inhibitor, also releases stored catecholamines

18
Q

What are the applications for amphetamines?

A

narcolepsy, obesity, ADHD

19
Q

How does cocaine work?

A

Indirect general agonist, reuptake inhibitor

20
Q

What are the effects of cocaine intox? What is contraindicated?

A

Vasoconstriction and local anesthesia. NEVER give beta-blockers, will lead to unopposed alpha1 activation and extreme hypertension.

21
Q

What does ephedrine work?

A

Indirect general agonist, releases stored catecholamines

22
Q

What are the applications for ephedrine?

A

Nasal decongestion, urinary incontinence, hypotension