Rational Drug Use Flashcards
0
Q
6 steps of rational prescribing
A
- Define problem
- Specify therapeutic objective
- Verify if P treatment is suitable for pt
- Start treatment
- Give info, instructions and warnings
- Monitor (stop) treatment
1
Q
Criteria needed to evaluate a p drug
A
Efficacy
Safety
Suitability
Cost
2
Q
Egs of special treatment groups
A
Elderly Paediatrics Pregnancy Lactation Renal dysfunction Liver dysfunction Porphyria Obesity Palliative care Sport Drug allergy Other
3
Q
Factors when determining P drug suitability
A
A - active substance and dosage form
B - standard dose schedule
C - standard duration of Rx
Effectiveness and safety
4
Q
3 ways to restore window/curve mismatch
A
Change the dose
Change the frequency
Change both
5
Q
What factors shift plasma concentration curve
A
ADME
6
Q
Steady state equals
A
4-5 times the half life
