Bacterial Infections of GI I Flashcards

1
Q

Diarrhea

A

passage of 3 or more loose or liquid stools per day

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2
Q

Gastritis

A

inflammation of stomach

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3
Q

Gastreoenteritis

A

inflammation of stomach and intestines

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4
Q

Dysentery

A

Diarrhea with blood and pus in feces

pain, fever, cramping

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5
Q

Enteritis

A

inflammatino of intestines, especially in small intestine

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6
Q

Enterocolitis

A

inflammation of the mucosa of the small and large intestine

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7
Q

Colitis

A

inflammation of large colon

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8
Q

What are some signs it’s an inflammatory GI bacteria

A

more likely to see fecal occult or visible clood

more likely to see fecal leukocytes

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9
Q

What are the 2 types of bacterial food poisoning

A

toxins produces by bacteria in food before it’s consumed

large numbers of spores ingested, which germinate in intestine

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10
Q

What are some symptoms of bacterial food poisoning

A

diarrhea, vomiting, or both - NO FEVER

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11
Q

What are the 4 bacteria causes of food poising

A

s. aureus
clostridium botulinum
clostridium perfringens
bacillus cereus

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12
Q

Characteristics of s. aureus

A

gram positive cocci in clusters

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13
Q

When does symptoms from food posioning from s. aureus start

A

1-8 hours after consumtion

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14
Q

Pathogenesis of s. aureus

A

heat stable toxin that is injected

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15
Q

Treatment for s. aureus food posioning

A

supportive treatment

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16
Q

Chacteristics of clostridium botulinum

A

spore forming
gram positive
rod

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17
Q

Early symptoms of clostridium botulinum

A

vomiting, diarrhea, cramping 1-8 hr after injustion or preformed toxin or 8-16 hours after ingestino of spores

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18
Q

Late symptoms of clostridium botulinum

A

flaccid paralysis, progressive muscle weakness & respiratory arrest

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19
Q

Botulism toxin

A

acts at neuromuscular nerve junctions, blocks acetylcholine release, inhibiting muscle stimulation

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20
Q

When do you often see clostridium botulinum

A

infants and honey

home-canning

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21
Q

Complications of clostridium botulinum

A

lingering weakness, dyspnea,

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22
Q

treatment of clostridium botulinum

A

supportive therapy, IV anti-toxin administration

23
Q

Infant botulism (floppy baby syndrome)

A

germiniation of c. botulinum spores in intestines
associated with honey
milder/lower morality than adult

24
Q

Clostridium perfringens

A

gram positive, rod

spore forming

25
Q

What is clostridium perfringens mediated by

A

c. perfringens enterotoxin

26
Q

What is clostridium perfringens associated with

A

meat products/gravies held at below recommended temps

27
Q

Symptoms of clostriudium perfringens

A

diarrhea/cramps 8-16 hours post ingestion, lasts 24 hrs

28
Q

What is the treatment for clostriudium perfringens

A

supportive therapy

29
Q

Characteristics of bacillus cereus

A

gram positive

spore forming

30
Q

Emetic form of bacillus cereus

A

ingestino of preformed heat-stable enterotoxin

onset of vomiting, nauseam cramping 1-8hr after injection

31
Q

What is the emetic form of bacillus cereus associated with

A

improper storage of cooked rice

32
Q

Diarrheal form of bacillus cereus

A

onset of diarrhea, nausea, cramps 8-16 hrs after injections

produces heat-liable enterotoxin in intestine

33
Q

Treatment of bacillus cereus

A

supportive therapy

34
Q

Characteristics of helicobacter pylori

A

gram negative, curved rod

microaerophilic

35
Q

What does helicobacter pylori casues

A

ulcers
chronic gastriitis
can lead to stomach cancers

36
Q

Pathogensis of helicobacter pylori

A

flagella
urease
cytotoxin-VacA
adhesins

37
Q

Diagnosis helicobacter pylori

A

urea breath test

biopsy

38
Q

How do you treat helicobacter pylori

A

antibiotics

proton pump inhibitor

39
Q

Listeria monocytogenes characteristics

A

gram positive, facultative anaerobic

short rods in pairs

40
Q

Survival traits of listeria monocytogenes

A

wide growth range
resistant to high salt
wide pH range

41
Q

Reservoirs of listeria monocytogenes

A

mammals, birds, fish

42
Q

What is the primary source of listeria monocytogenes

A

ready to eat meats, raw veggies

43
Q

How is listeria monocytogenes spread from person to person

A

mother to fetus

44
Q

Symptoms of listeria monocytogenes in healthy adults

A

usually asymptomatic, may have fever, nausea, diarrhea

45
Q

listeria monocytogenes can cause what in immunocompromised adults

A

bacteremia
meningitis
encephalitis

46
Q

What are symptoms of listeria monocytogenes in pregnant woman

A

key sign is fever with no obvious infection

also may develop nausea, fever, diarrhea

47
Q

What can listeria monocytogenes cause in infants

A

granulomatosis infantiseptica
meningitis
encephalitis

48
Q

granulomatosis infantiseptica

A

pyogenic granulomas distributed all over body

49
Q

Pathogenesis of listeria monocytogenes

A

adherence and induced uptake mediated by internalin-A
internalized into endocytic vacuole
acidification of vacuole/phagosome activates listeriolysin O
Replicatio nin host cell cytosol
ActA mediated actin polymerixation
Disseminated infection

50
Q

Where can listeria monocytogenes spread to

A

liver, spleen, CNS

51
Q

How do you detect listeria monocytogenes

A

cold enrichment selection
look for beta hemolysis
motility test

52
Q

How do you treat listeria monocytogenes

A

bacta lactam or trimethoprim-sulfamethoxazole

53
Q

How do you prevent listeria monocytogenes

A

no vax

cook food properly