Damage to basal ganglia

Question 1

Parkinson’s

Answer 1

Substantia nigra pars compacta cells are dead or lost

Lose regulation of initiation of movement

Question 2

Huntington’s

Answer 2

Severe loss of internal capsule, corona radiata, caudate, putamen
Results in flailing movements

Question 3

Tourette’s

Answer 3

Lower threshold for initiating movement

Initiate too easily, resulting in tics and random shouting

Question 4

Schizophrenia

Answer 4

Dysregulation of dopamine