Dentin 2

Question 1

Dental pulp

Answer 1

highly cellularized
fibroblasts followed by OD
arises from dental papilla- ectomesychymal tissue
OD layer, cell free zone, cell rich, pulp core

Question 2

dental pulp ECM

Answer 2

soft CT matrix, mostly type 3 collagen and collagen 1, proteoglycans and glycoproteins
ground substance: proteoglycans, water

Question 3

Odontoblasts

Answer 3

polarized, elongated nucleus on pulpal side, secretory components (golgi bodies) towards dentin
at root they are more cuboidal
form ta discrete layer held together by adherens junctions
sequester growth factors
older= less organelles, less secretory activity, nucleus more central
can be replaced by mesenchymal progenitor pool

Question 4

fibroblast

Answer 4

predominant cell type in dentin-pulp complex

found in pulp core and cell rich

Question 5

immune cells

Answer 5

macrophages in pulp
dendritic cells: antigen presenters to T cells, found under OD layer- closely associated with neuronal and vascular components
t and B lymphocytes in infected pulp

Question 6

vascular supply

Answer 6

arises from external coarotid and branches to sup/inf alveolar arteries
4-8 arterioles per root
as arterioles proceed into pulp the caliber increases and vessel wall decreases
anastomose in cell free zone
eventually get to internal jugular vein

Question 7

innervation

Answer 7

nerve fibers branch forming plexus of raschkow
incoming from trigeminal and sympathertics from superior cervical ganglion
mylenation decreases as fibers proceed coronally

Question 8

pulp stones

Answer 8

mineralized tissue in pulp
free- surrounded by pulp
attached- bound to dentin
embedded- surrounded by seconday dentin
true- contains tubules
false- no tubules

Question 9

age related change in pulp

Answer 9

cell number decreases, pulp receeds
decrease in permeability
more brittle teeth
loose neurons
more collagen calcifies