Quiz 2 Flashcards
Which has the most cells: enamel, dentin, pulp?
Pulp
How much % of dentin is “inorganic” material?
70%
How much % of dentin is “organic” material?
20%
How much of dentin is water?
10%
What is intertwined around the dentinal tubules?
Collagen fibers (banded)
What does mineralized dentin versus un-mineralized dentin look like?
Un-mineralized dentin looks like a lot of circular fibers, no structure.
Mineralized looks like solid dentin tubules
What main type of collagen is in Dentin?
Type I Collagen
What’s the purpose of the collagen in dentin?
It’s the fiber scaffold for HA crystals
What’s the purpose of the non-collagenous protein in dentin?
helps with laying down mineral, and making sure it’s happening in the right places.
What are the “main 2” proteins found in dentin?
Dentin Matrix Protein 1 (mineralizes dentin) Dentin SialoPhosphoProtein (3 more parts)
What does DSPP further cleave into?
- Dentin SialoProtein (DSP)
- Dentin PhosphoProtein (DPP)
- Dentin GlycoProtein (DG)
Are the proteins found in Dentin also found in bone?
YES!! in a smaller amount.
Where is DSP found and what does it do?
It’s in the tubules, and it doesn’t allow mineral to build up in the initial phase.
What does DGP do?
It helps with the mineralization (but somewhat unknown)
What does DPP do?
It helps with crystal formation
What could a defect in DSPP cause?
dentinogenesis imperfecta Types 2/3
What happens to the pulp with dentinogenesis imperfecta type 1-2?
The pulp gets filled with abnormal dentin
What happens with dentinogenesis imperfecta type 3?
large pulp chambers,hypomineralizeation (Dspp didn’t work)
What cell makes dentin?
Odontoblasts